Systematic Review and Meta-Analysis of the Clinical Utility of the ADOS-2 and the ADI-R in Diagnosing Autism Spectrum Disorders in Children.

The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) and the Autism Diagnostic Interview, Revised (ADI-R) have high accuracy as diagnostic instruments in research settings, while evidence of accuracy in clinical settings is less robust. This meta-analysis focused on efficacy of these...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 51; no. 11; pp. 4101 - 4115
Autores principales: Lebersfeld, Jenna B., Swanson, Marissa, Clesi, Christian D., O'Kelley, Sarah E.
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2021
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      pub: Springer Nature
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        10.1007/s10803-020-04839-z
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        atl: Systematic Review and Meta-Analysis of the Clinical Utility of the ADOS-2 and the ADI-R in Diagnosing Autism Spectrum Disorders in Children.
      aug:
        au:
          Lebersfeld, Jenna B.
          Swanson, Marissa
          Clesi, Christian D.
          O'Kelley, Sarah E.
        affil: University of Alabama at Birmingham, 1720 7th Ave S, 35233, Birmingham, AL, USA
      sug:
        subj:
          Autism Spectrum Disorder Diagnosis
          Psychological Tests
          Human
          Systematic Review
          Meta Analysis
          ROC Curve
          Sensitivity and Specificity
          Validity
      ab: The Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) and the Autism Diagnostic Interview, Revised (ADI-R) have high accuracy as diagnostic instruments in research settings, while evidence of accuracy in clinical settings is less robust. This meta-analysis focused on efficacy of these measures in research versus clinical settings. Articles (n = 22) were analyzed using a hierarchical summary receiver operating characteristics (HSROC) model. ADOS-2 performance was stronger than the ADI-R. ADOS-2 sensitivity and specificity ranged from.89-.92 and.81-.85, respectively. ADOS-2 accuracy in research compared with clinical settings was mixed. ADI-R sensitivity and specificity were.75 and.82, respectively, with higher specificity in research samples (Research =.85, Clinical =.72). A small number of clinical studies were identified, indicating ongoing need for investigation outside research settings.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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