Photobiomodulation Enhances Memory Processing in Older Adults with Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy Study.
Background: Recent studies of photobiomodulation (PBM) in patients with cognitive or psychological disorders (including traumatic brain injury, stroke, and dementia) have yielded some encouraging results.Objective: In this study, we aimed to investigate the effect of a single stimulation on memory i...
| Publicado en: | Journal of Alzheimer's Disease Vol. 83; no. 4; pp. 1471 - 1481 |
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| Autores principales: | , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=153068018&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 153068018 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13872877 FLR jtl: Journal of Alzheimer's Disease issn: 13872877 maglogo: N pubinfo: dt: 2021 vid: 83 iid: 4 pid: 20732 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 153068018 153068018 NLM33998541 153068018 10.3233/JAD-201600 NLM33998541 153068018 ppf: 1471 ppct: 10 formats: tig: atl: Photobiomodulation Enhances Memory Processing in Older Adults with Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy Study. aug: au: Chan, Agnes S. Lee, Tsz-lok Hamblin, Michael R. Cheung, Mei-chun affil: Department of Psychology, The Chinese University of Hong Kong, Hong Kong, China sug: subj: Spectroscopy, Near-Infrared Memory, Short Term Neuropsychological Tests Statistics and Numerical Data Aged Female Human Male Hemodynamics Radiation Effects Cognition Comparative Studies Multicenter Studies Evaluation Research Validation Studies Aged: 65+ years Female Male ab: Background: Recent studies of photobiomodulation (PBM) in patients with cognitive or psychological disorders (including traumatic brain injury, stroke, and dementia) have yielded some encouraging results.Objective: In this study, we aimed to investigate the effect of a single stimulation on memory in older adults with mild cognitive impairment (MCI).Methods: After PBM, hemodynamic changes, as a measure of functional brain activity, were evaluated using functional near-infrared spectroscopy (fNIRS). Eighteen subjects who met the criteria of MCI were randomly assigned to control and experimental groups. A single real or sham PBM session was administered to the forehead of each patient in the experimental and control groups, respectively. All subjects performed a visual memory span test before and after the stimulation, and their hemodynamic responses during the tasks were measured using fNIRS.Results: The results showed that among the MCI subjects, only those who received PBM, but not those who received the sham stimulation, demonstrated significant improvement in the visual memory performance and a reduction in the hemodynamic response during the tasks.Conclusion: These findings suggest that PBM may reduce the cognitive efforts needed to complete tasks that require high memory loads, and thus improve the cognitive performance of individuals with MCI. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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