Employing multiple synchronous outcome samples per subject to improve study efficiency.

Background: Accuracy can be improved by taking multiple synchronous samples from each subject in a study to estimate the endpoint of interest if sample values are not highly correlated. If feasible, it is useful to assess the value of this cluster approach when planning studies. Multiple assessments...

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Bibliographic Details
Published in:BMC Medical Research Methodology Vol. 21; no. 1; pp. 1 - 12
Main Author: A'Hern, Roger P.
Format: equations & formulas research tables/charts Journal Article
Published: BioMed Central 10/17/2021
Online Access:View this record in EBSCOhost