Vitamin A status and recurrent respiratory infection among Chinese children: A nationally representative survey.

Background and Objectives: Vitamin A is involved in immune function, vision, reproduction, and cell differentiation and is essential for child growth. Vitamin A deficiency (VAD) contributes significantly to mortality and morbidity in developing countries. This study assessed the current vitamin A st...

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Published in:Asia Pacific Journal of Clinical Nutrition Vol. 29; no. 3; pp. 566 - 577
Main Authors: Zhang, Yixin, Du, Zifang, Ma, Wenbo, Chang, Keliang, Zheng, Chunmei
Format: research Journal Article
Published: Qingdao University Sep2020
Online Access:View this record in EBSCOhost
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        09647058
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      jtl: Asia Pacific Journal of Clinical Nutrition
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      dt: Sep2020
      vid: 29
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      pub: Qingdao University
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        153306148
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        10.6133/apjcn.202009_29(3).0016
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        153306148
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        atl: Vitamin A status and recurrent respiratory infection among Chinese children: A nationally representative survey.
      aug:
        au:
          Zhang, Yixin
          Du, Zifang
          Ma, Wenbo
          Chang, Keliang
          Zheng, Chunmei
        affil: Department of Statistics, Renmin University of China, Beijing, China
      sug:
        subj:
          Vitamin A Blood
          Vitamin A Deficiency Epidemiology
          Child
          Adolescence
          Infant
          Child, Preschool
          Female
          Male
          Nutritional Status
          China
          Cross Sectional Studies
          Human
          Child: 6-12 years
          Adolescent: 13-18 years
          Infant: 1-23 months
          Child, Preschool: 2-5 years
          Female
          Male
      ab: Background and Objectives: Vitamin A is involved in immune function, vision, reproduction, and cell differentiation and is essential for child growth. Vitamin A deficiency (VAD) contributes significantly to mortality and morbidity in developing countries. This study assessed the current vitamin A status in Chinese children.Methods and Study Design: A cross-sectional survey was conducted in 26 provinces in China between 2015 and 2018, and 277,064 children aged 0-14 years were enrolled. Data on sociodemographic factors and dietary supplements were obtained through interviews with their parents. Serum vitamin A concentrations were measured using HPLC. To reduce the sampling error, a weighted distribution was produced to estimate the distribution of serum vitamin A concentration in Chinese children. A new method was used calculate the CI.Results: The results revealed that 10.4% (23.9 million) (95% CI: 10.1%-10.8%) of Chinese children aged 0-14 years were at risk of suffering from subclinical VAD (SVAD) (<0.2 mg/L). Sick children, especially those with recurrent respiratory infections (21.3%, 95% CI: 20.5%-22.2%), were vulnerable to SVAD. A high prevalence of SVAD was observed in western and northeastern areas in China. Serum vitamin A concentrations in ethnic minority groups were significantly lower than those in Han Chinese children (p<0.01).Conclusions: VAD is still a moderate public health problem in Chinese children, especially in those with respiratory symptoms. Regular consumption of vitamin A-rich foods should be promoted through nutrition education for parents.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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