A predictive model incorporating the change detection and Winsorization methods for alerting hypoglycemia and hyperglycemia.

This paper focuses on establishing an effective predictive model to quickly and accurately alert hypoglycemia and hyperglycemia for helping control blood glucose levels of people with diabetes. In general, a good predictive model is established on the features of data. Inspired by this, we first ana...

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Publicado en:Medical & Biological Engineering & Computing Vol. 59; no. 11/12; pp. 2311 - 2325
Autores principales: Li, Lei, Xie, Xiaolei, Yang, Jun
Formato: Journal Article
Publicado: Springer Nature Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2021
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      pub: Springer Nature
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        10.1007/s11517-021-02433-8
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        atl: A predictive model incorporating the change detection and Winsorization methods for alerting hypoglycemia and hyperglycemia.
      aug:
        au:
          Li, Lei
          Xie, Xiaolei
          Yang, Jun
        affil: School of Reliability and Systems Engineering, Beihang University, 100191, Beijing, People's Republic of China
      sug:
        subj:
          Hypoglycemia Diagnosis
          Diabetes Mellitus
          Diabetes Mellitus, Type 1
          Hyperglycemia Diagnosis
          Blood Glucose Self-Monitoring
          Blood Glucose
          Questionnaires
      ab: This paper focuses on establishing an effective predictive model to quickly and accurately alert hypoglycemia and hyperglycemia for helping control blood glucose levels of people with diabetes. In general, a good predictive model is established on the features of data. Inspired by this, we first analyze the characteristics of continuous glucose monitoring (CGM) data by the equality of variances test and outlier detection, which show time-varying fluctuations and jump points in CGM data. Therefore, we incorporate the change detection method and the Winsorization method into the predictive model based on the autoregressive moving average (ARMA) model and the recursive least squares (RLS) method to fit the above characteristics. To the best of our knowledge, the proposed method is the first attempt to give a solution for matching the time-varying fluctuations and jump points of CGM data simultaneously. A case study using CGM data is given to validate the effectiveness of the proposed method under 30-min-ahead prediction. The results show that the proposed method can improve the true alarm ratio of hypoglycemia and hyperglycemia from 0.7983 to 0.8783, and lengthen the average advance detection time of hypoglycemia and hyperglycemia from 19.77 to 22.64 min.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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