Effectiveness of broad‐spectrum antiseptics in production of disinfected maggots of Lucilia sericata for use in wound debridement therapy.

The establishment of low‐cost, effective, safe and practical methods is necessary to increase the use of larval therapy in wound care. Although studies on external disinfection of calliphorid eggs have been reported, many studies lack data on the effect of disinfection on egg viability and the micro...

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Publicado en:Wound Repair & Regeneration Vol. 29; no. 6; pp. 1017 - 1024
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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    uiTag: AN
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        10671927
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      jtl: Wound Repair & Regeneration
      issn: 10671927
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      dt: Nov2021
      vid: 29
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/wrr.12968
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        atl: Effectiveness of broad‐spectrum antiseptics in production of disinfected maggots of Lucilia sericata for use in wound debridement therapy.
      aug:
      sug:
        subj:
          Antiinfective Agents, Local
          Larva
          Larval Therapy
          Wound Care
          Sterilization and Disinfection
          Chlorhexidine
          Povidone-Iodine
          Eggs
      ab: The establishment of low‐cost, effective, safe and practical methods is necessary to increase the use of larval therapy in wound care. Although studies on external disinfection of calliphorid eggs have been reported, many studies lack data on the effect of disinfection on egg viability and the microorganisms found before disinfection. Therefore, the main objective of this study was to compare three antiseptic solutions, that is, chlorhexidine (5%), Dakin's solution (0.5% NaOCl) and povidone‐iodine (10%), in terms of their ability to disinfect Lucilia sericata eggs. Egg viability after disinfection and microorganisms present on the eggs and larvae before and after treatment were also examined. None of the antiseptics had a significant effect on egg viability. Disinfection of L. sericata eggs with 0.5% NaOCl was the best method, as sterility tests showed no contamination. Escherichia coli, Bacillus subtilis and Proteus mirabilis were present in all cultures isolated from the non‐disinfected eggs and larvae, while Enterococcus faecium, Enterococcus faecalis, Morganella morganii, Corynebacterium spp. and Providencia stuartii were isolated from more than half of the same cultures. Sterility testing of medicinal maggots after disinfection is crucial to prevent secondary infections and achieve a positive therapeutic outcome.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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