Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis.
Purpose: Yeast β-glucans are known for their immune-modulating effects; however, their effects on human upper respiratory tract infections (URTIs) remain unclear. The aim of the present study was to use a systematic review and meta-analysis approach to investigate the effects of yeast β-glucans for...
| Publicado en: | European Journal of Nutrition Vol. 60; no. 8; pp. 4175 - 4188 |
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| Autores principales: | , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Dec2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=153436524&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 153436524 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Dec2021 vid: 60 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 153436524 150000235 153436524 153436524 10.1007/s00394-021-02566-4 153436524 ppf: 4175 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Effects of yeast β-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. aug: au: Zhong, Kunxia Liu, Zhiqin Lu, Yao Xu, Xi affil: Center for Molecular Metabolism, Nanjing University of Science and Technology, 200 Xiaolingwei Street, 210094, Nanjing, People's Republic of China sug: subj: Respiratory Tract Infections Prevention and Control Yeasts beta-Glucans Therapeutic Use Treatment Outcomes Human Systematic Review Meta Analysis PubMed Embase Cochrane Library Odds Ratio Confidence Intervals Incidence Comparative Studies ab: Purpose: Yeast β-glucans are known for their immune-modulating effects; however, their effects on human upper respiratory tract infections (URTIs) remain unclear. The aim of the present study was to use a systematic review and meta-analysis approach to investigate the effects of yeast β-glucans for the prevention and treatment of URTIs in healthy subjects. Methods: Databases including Pubmed, Web of Science, EMBASE and the Cochrane Library were searched and 13 RCTs investigating the effects of yeast β-glucans on the incidence, duration, and severity of URTIs in healthy subjects were included. Results: The results showed that compared to the placebo group, yeast β-glucan could significantly reduce the incidence of URTIs (OR = 0.345, 95% CI = 0.192 to 0.620, p < 0.001), decrease the average number of URTI episodes (SMD = − 0.315, 95% CI = − 0.500 to − 0.130, p < 0.05), and decrease the duration of URTIs (SMD = − 0.312, 95% CI = − 0.561 to − 0.064, p < 0.001). Improved severity of symptoms was found in yeast β-glucan group compared to the placebo group in the majority of included studies. In addition, yeast β-glucan was well tolerated and safe in general. Conclusion: These findings suggest a positive effect of yeast β-glucans on human URTIs. However, due to the high heterogeneity and small number of included studies, more high-quality research and clinical trials are warranted. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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