Association of herpes zoster and chronic inflammatory skin disease in US inpatients.
Background: Patients with chronic inflammatory skin disease (CISD) have potential risk factors for herpes zoster (HZ). However, little is known about HZ risk in CISD.Objective: To determine whether CISD is associated with HZ.Methods: Data were analyzed from the 2002 to 2012 Nationwide Inpatient Samp...
| Publicado en: | Journal of the American Academy of Dermatology Vol. 85; no. 6; pp. 1437 - 1446 |
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| Autores principales: | , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
Dec2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=153480739&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 153480739 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Dec2021 vid: 85 iid: 6 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 153480739 153480739 NLM31958523 10.1016/j.jaad.2019.12.073 NLM31958523 153480739 ppf: 1437 ppct: 9 formats: tig: atl: Association of herpes zoster and chronic inflammatory skin disease in US inpatients. aug: au: Chovatiya, Raj Silverberg, Jonathan I. affil: Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois sug: subj: Hospitalization Statistics and Numerical Data Dermatitis Epidemiology Skin Diseases Epidemiology Dermatitis, Atopic Epidemiology Herpes Zoster Epidemiology Child, Preschool Inpatients Dermatitis Immunology Skin Diseases Immunology Infant, Newborn Infant Child Dermatitis, Atopic Immunology Young Adult Aged Female Chronic Disease Middle Age Cross Sectional Studies Adult Adolescence Child, Preschool: 2-5 years Infant, Newborn: birth-1 month Infant: 1-23 months Child: 6-12 years Aged: 65+ years Middle Aged: 45-64 years Adult: 19-44 years Adolescent: 13-18 years Female ab: Background: Patients with chronic inflammatory skin disease (CISD) have potential risk factors for herpes zoster (HZ). However, little is known about HZ risk in CISD.Objective: To determine whether CISD is associated with HZ.Methods: Data were analyzed from the 2002 to 2012 Nationwide Inpatient Sample, a representative cohort of US hospitalizations (N = 68,088,221 children and adults).Results: In multivariable logistic regression models including age, sex, race/ethnicity, insurance, household income, and long-term systemic corticosteroid use, hospitalization for HZ was associated with atopic dermatitis (adjusted odds ratio [95% confidence interval], 1.38 [1.14-1.68]), psoriasis (4.78 [2.83-8.08]), pemphigus (1.77 [1.01-3.12]), bullous pemphigoid (1.77 [1.01-3.12]), mycosis fungoides (3.79 [2.55-5.65]), dermatomyositis (7.31 [5.27-10.12]), systemic sclerosis (1.92 [1.47-2.53]), cutaneous lupus erythematosus (1.94 [1.10-3.44]), vitiligo (2.00 [1.04-3.85]), and sarcoidosis (1.52 [1.22-1.90]). Only lichen planus (crude odds ratio [95% confidence interval], 3.01 [1.36-6.67]), Sézary syndrome (12.14 [5.20-28.31]), morphea (2.74 [1.36-5.51]), and pyoderma gangrenosum (2.44 [1.16-5.13]) showed increased odds in bivariable models. Sensitivity analyses among those younger than 60 and younger than 50 years showed similar results. Predictors of HZ in CISD included female sex, fewer chronic conditions, and long-term systemic corticosteroid use.Limitations: Cross-sectional study.Conclusions: Many CISDs are associated with increased hospitalization for HZ, even below the ages recommended for HZ vaccination. Additional studies are needed to establish CISD-specific vaccination guidelines. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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