CloneRetriever: An Automated Algorithm to Identify Clonal B and T Cell Gene Rearrangements by Next-Generation Sequencing for the Diagnosis of Lymphoid Malignancies.

BACKGROUND: Clonal immunoglobulin and T-cell receptor rearrangements serve as tumor-specific markers that have become mainstays of the diagnosis and monitoring of lymphoid malignancy. Next-generation sequencing (NGS) techniques targeting these loci have been successfully applied to lymphoblastic leu...

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Bibliographic Details
Published in:Clinical Chemistry Vol. 67; no. 11; pp. 1524 - 1534
Main Authors: Halper-Stromberg, Eitan, McCall, Chad M., Haley, Lisa M., Ming-Tseh Lin, Vogt, Samantha, Gocke, Christopher D., Eshleman, James R., Stevens, Wendy, Martinson, Neil A., Epeldegui, Marta, Holdhoff, Matthias, Bettegowda, Chetan, Glantz, Michael J., Ambinder, Richard F., Xian, Rena R.
Format: Journal Article
Published: Oxford University Press / USA Nov2021
Online Access:View this record in EBSCOhost