Multimorbid disease trajectories for people with periodontitis.
Aim: Periodontitis is a multifactorial condition linked to increased risk of systemic diseases. This study aimed to identify disease trajectories of people with periodontitis using the process mining technique as a heuristic approach. Materials and methods: A total of 188,863 participants from the U...
| Publicado en: | Journal of Clinical Periodontology Vol. 48; no. 12; pp. 1587 - 1597 |
|---|---|
| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2021
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=153674793&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 153674793 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03036979 8E3 jtl: Journal of Clinical Periodontology issn: 03036979 maglogo: Y pubinfo: dt: Dec2021 vid: 48 iid: 12 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 153674793 152724031 153674793 153674793 10.1111/jcpe.13536 153674793 ppf: 1587 ppct: 10 formats: tig: atl: Multimorbid disease trajectories for people with periodontitis. aug: au: Larvin, Harriet Kang, Jing Aggarwal, Vishal R. Pavitt, Sue Wu, Jianhua affil: School of Dentistry, University of Leeds, Leeds, UK sug: subj: Periodontitis Disease Progression Risk Factors Noncommunicable Diseases Risk Factors Comorbidity Risk Factors Noncommunicable Diseases Epidemiology Comorbidity Epidemiology Noncommunicable Diseases Mortality Risk Assessment Human United Kingdom Self Report Oral Health Relative Risk Cox Proportional Hazards Model Matched Case Control Confidence Intervals Cardiovascular Diseases Depression Descriptive Statistics ab: Aim: Periodontitis is a multifactorial condition linked to increased risk of systemic diseases. This study aimed to identify disease trajectories of people with periodontitis using the process mining technique as a heuristic approach. Materials and methods: A total of 188,863 participants from the UK Biobank cohort were included. Self‐reported oral health indicators (bleeding gums, painful gums, loose teeth) were surrogates for periodontitis at baseline. Systemic disease diagnoses and dates formed the process mining event log. Relative risk (RR) of systemic diseases, disease trajectories, and Cox proportional hazard ratio models for mortality were compared to age‐ and sex‐matched controls who did not report a history of periodontitis. Results: Participants with loose teeth had shorter median time to most systemic diseases, and crude RR was increased for several diseases including cardiovascular disease (crude RR: 1.15, 95% CI: 1.03–1.28), hypertension (crude RR: 1.14, 95% CI: 1.05–1.24), and depression (crude RR: 1.33, 95% CI: 1.09–1.61). Participants with loose teeth had increased RR for 20 disease trajectories, though these were not significant after adjustments. Participants with bleeding/painful gums had similar disease trajectories as those of matched controls. Conclusions: Self‐reported periodontitis may be associated with early and frequent multimorbidity development, though further evidence is required to confirm this hypothesis. People with periodontitis should be informed of the risks of disease progression and be targeted in prevention initiatives. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|