Synthesis of standard 12‑lead electrocardiograms using two-dimensional generative adversarial networks.

This paper proposes a two-dimensional (2D) bidirectional long short-term memory generative adversarial network (GAN) to produce synthetic standard 12-lead ECGs corresponding to four types of signals-left ventricular hypertrophy (LVH), left branch bundle block (LBBB), acute myocardial infarction (ACU...

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Publicado en:Journal of Electrocardiology Vol. 69; pp. 6 - 15
Autores principales: Zhang, Yu-He, Babaeizadeh, Saeed
Formato: Journal Article
Publicado: W B Saunders Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2021
      vid: 69
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      pub: W B Saunders
      place: Philadelphia, Pennsylvania
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        10.1016/j.jelectrocard.2021.08.019
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        atl: Synthesis of standard 12‑lead electrocardiograms using two-dimensional generative adversarial networks.
      aug:
        au:
          Zhang, Yu-He
          Babaeizadeh, Saeed
        affil: Advanced Algorithm Research Center, Philips Healthcare, Cambridge, MA, USA
      sug:
        subj:
          Electrocardiography
          Myocardial Infarction
          Generative Adversarial Networks
          Resource Databases
          Bundle-Branch Block
          Hypertrophy, Left Ventricular Diagnosis
      ab: This paper proposes a two-dimensional (2D) bidirectional long short-term memory generative adversarial network (GAN) to produce synthetic standard 12-lead ECGs corresponding to four types of signals-left ventricular hypertrophy (LVH), left branch bundle block (LBBB), acute myocardial infarction (ACUTMI), and Normal. It uses a fully automatic end-to-end process to generate and verify the synthetic ECGs that does not require any visual inspection. The proposed model is able to produce synthetic standard 12-lead ECG signals with success rates of 98% for LVH, 93% for LBBB, 79% for ACUTMI, and 59% for Normal. Statistical evaluation of the data confirms that the synthetic ECGs are not biased towards or overfitted to the training ECGs, and span a wide range of morphological features. This study demonstrates that it is feasible to use a 2D GAN to produce standard 12-lead ECGs suitable to augment artificially a diverse database of real ECGs, thus providing a possible solution to the demand for extensive ECG datasets.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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