Heterogeneity in DSM-5 Symptom Criteria: Phenotypes of Alcohol Use Disorder in a Sample Seeking Alcohol Treatment.

Aims This study sought to identify phenotypic variations among individuals with alcohol use disorder (AUD) that may, in part, help improve the effectiveness of existing AUD interventions. Methods Latent class analysis was conducted to examine the potential heterogeneity of AUD in a sample (N  = 220;...

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Publicado en:Alcohol & Alcoholism Vol. 56; no. 6; pp. 660 - 669
Autores principales: Zhao, Junru, Linn, Braden, Bradizza, Clara, Lucke, Joseph, Ruszczyk, Melanie, Stasiewicz, Paul
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2021
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      pub: Oxford University Press / USA
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        10.1093/alcalc/agaa138
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        atl: Heterogeneity in DSM-5 Symptom Criteria: Phenotypes of Alcohol Use Disorder in a Sample Seeking Alcohol Treatment.
      aug:
        au:
          Zhao, Junru
          Linn, Braden
          Bradizza, Clara
          Lucke, Joseph
          Ruszczyk, Melanie
          Stasiewicz, Paul
        affil: School of Social Work , University at Buffalo—The State University of New York, 1021 Main Street, Buffalo, NY 14203, USA
      sug:
        subj:
          Alcohol Abuse Symptoms
          DSM
          Alcohol Abuse Therapy
          Phenotype
          Human
          Persons with Substance Use Disorders
          Latent Structure Analysis
          Middle Age
          Male
          Female
          Adult
          Socioeconomic Factors
          Descriptive Statistics
          Individualized Medicine
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Male
          Female
      ab: Aims This study sought to identify phenotypic variations among individuals with alcohol use disorder (AUD) that may, in part, help improve the effectiveness of existing AUD interventions. Methods Latent class analysis was conducted to examine the potential heterogeneity of AUD in a sample (N  = 220; M age = 51.19 years, standard deviation = 9.94; 37.7% female) of treatment-seeking participants diagnosed with AUD using DSM-5 criteria. Results and Conclusions Three distinct patterns of responses to the 11 DSM-5 AUD symptoms emerged: Class 1 (n  = 114, 51.8%), Class 2 (n  = 78, 35.5%) and Class 3 (n  = 28, 12.7%). The identified profiles were further differentiated by demographics, alcohol-related constructs, individual difference characteristics and diagnostic and treatment variables. The findings have implications for refining AUD assessment as well as optimizing personalized treatment.
      pubtype: Academic Journal
      doctype:
        research
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      ougenre: Article
    language: English
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