Protect Effects of Seafood-Derived Plasmalogens Against Amyloid-Beta (1–42) Induced Toxicity via Modulating the Transcripts Related to Endocytosis, Autophagy, Apoptosis, Neurotransmitter Release and Synaptic Transmission in SH-SY5Y Cells.

To investigate the underlying mechanisms of decreased plasmalogens (Pls) levels in neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and differentiated human SH-SY5Y neuroblastoma cells exposed to amyloid-β1–42 was analyzed. Transcriptional profiles indicated th...

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Detalles Bibliográficos
Publicado en:Frontiers in Aging Neuroscience Vol. 13; pp. 1 - 13
Autores principales: Feng, Junli, Song, Gongshuai, Shen, Qing, Chen, Xi, Wang, Qingcheng, Guo, Shunyuan, Zhang, Manman
Formato: Journal Article
Publicado: Frontiers Media S.A. 11/26/2021
Acceso en línea:Ver este registro en EBSCOhost