Left atrial reservoir strain provides incremental value to left atrial volume index for evaluation of left ventricular filling pressure.

Background: Left atrial analysis is employed in diastolic assessment with left atrial volume index (LAVI) incorporated in the 2016 ASE/EACVI diastology guideline algorithm. LAVI has sub‐optimal correlation with invasive left ventricular filling pressure (LVFP) and incorporation of left atrial reserv...

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Publicado en:Echocardiography Vol. 38; no. 9; pp. 1503 - 1514
Autores principales: Tomlinson, Stephen, Scalia, Gregory M., Appadurai, Vinesh, Edwards, Natalie, Savage, Michael, Lam, Alfred K‐Y., Chan, Jonathan
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Sep2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2021
      vid: 38
      iid: 9
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.15157
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        atl: Left atrial reservoir strain provides incremental value to left atrial volume index for evaluation of left ventricular filling pressure.
      aug:
        au:
          Tomlinson, Stephen
          Scalia, Gregory M.
          Appadurai, Vinesh
          Edwards, Natalie
          Savage, Michael
          Lam, Alfred K‐Y.
          Chan, Jonathan
        affil: Department of Cardiology, The Prince Charles Hospital, Brisbane, Australia
      sug:
        subj:
          Heart Atrium, Left Physiopathology
          Atrial Fibrillation
          Ventricular Dysfunction, Left Physiopathology
          Ventricular Pressure
          Human
          Cross Sectional Studies
          Prospective Studies
          Echocardiography
          Descriptive Statistics
          Algorithms
          Male
          Female
          Middle Age
          Aged
          ROC Curve
          Sensitivity and Specificity
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Left atrial analysis is employed in diastolic assessment with left atrial volume index (LAVI) incorporated in the 2016 ASE/EACVI diastology guideline algorithm. LAVI has sub‐optimal correlation with invasive left ventricular filling pressure (LVFP) and incorporation of left atrial reservoir strain (LASr) may improve diastolic assessment. Methods: A cross‐sectional prospective study of 139 patients was undertaken with all patients undergoing transthoracic echocardiography immediately prior to cardiac catheterization with invasive evaluation of LVFP. LASr by speckle tracking echocardiography and conventional echocardiographic parameters were assessed in relation to invasive LVFP. Modification of the 2016 guideline algorithm was performed with incorporation of LASr in place of LAVI (LASr ≤23% indicating elevated LVFP). Accuracy of the modified and conventional algorithm were assessed for predicting invasive LVFP. Results: The mean age was 63±12 years with 27% female. LASr demonstrated superior correlation and receiver operator characteristic for predicting LVFP than LAVI (LASr: r ‐.46 (p < 0.01), AUC:.82 vs LAVI: r.19 (p 0.02), AUC:.66). LASr of ≤23% was the optimal cut‐off for discriminating elevated LVFP (sensitivity 80%, specificity 77%). Modification of the 2016 algorithm with incorporation of LASr in place of LAVI reclassified 12% of the patient cohort and improved concordance of echocardiographic and invasive LVFP assessment (modified algorithm κ.47 vs 2016 algorithm κ:.33). No patients were incorrectly reclassified by modified algorithm assessment. Conclusions: LASr better predicts invasive LVFP than LAVI. Modification of the 2016 guideline algorithm with incorporation of LASr in place of LAVI improves accuracy of echocardiographic assessment of LVFP.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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