Quantitative evaluation of fetal ventricular function by speckle tracking echocardiography.

Methods: The study included 59 patients with normal fetal heart structure, blood flow, and heart rhythm (fetal abnormality‐negative group) and 50 patients with abnormal fetal heart structure, blood flow, and/or heart rhythm (fetal abnormality‐positive group). Automated Cardiac Motion Quantification...

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Published in:Echocardiography Vol. 38; no. 11; pp. 1924 - 1932
Main Authors: Luo, Ling, Liu, Hanmin, Zhou, Shu, Zhao, Fumin, Zhu, Qi, Guo, Nan, Chen, Jiao
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell Nov2021
Online Access:View this record in EBSCOhost
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      dt: Nov2021
      vid: 38
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.15240
        153878028
      ppf: 1924
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        atl: Quantitative evaluation of fetal ventricular function by speckle tracking echocardiography.
      aug:
        au:
          Luo, Ling
          Liu, Hanmin
          Zhou, Shu
          Zhao, Fumin
          Zhu, Qi
          Guo, Nan
          Chen, Jiao
        affil: Department of Ultrasonic Medicine, West China Second University Hospital of Sichuan University, Chengdu Sichuan,, China
      sug:
        subj:
          Heart Ventricle Physiology
          Echocardiography Methods
          Myocardium
          Blood Circulation
          Heart Rate
          Human
          Correlational Studies
          Reproducibility of Results
          Interrater Reliability
          Intraclass Correlation Coefficient
      ab: Methods: The study included 59 patients with normal fetal heart structure, blood flow, and heart rhythm (fetal abnormality‐negative group) and 50 patients with abnormal fetal heart structure, blood flow, and/or heart rhythm (fetal abnormality‐positive group). Automated Cardiac Motion Quantification (aCMQ) was performed in both groups to obtain left and right ventricular endocardial global longitudinal strain (GLSendo), mid‐myocardial global longitudinal strain (GLSmid), and epicardial global longitudinal strain (GLSepi). Parameters between the two groups were compared and correlation analyses performed. A deformation analysis was performed by two trained observers, and reproducibility was assessed. Results: The fetal left ventricular and right ventricular global longitudinal strain (LV‐GLS and RV‐GLS, respectively) decreased in a gradient from the endocardium to the epicardium. LV‐GLS and RV‐GLS of all myocardial layers were lower in the fetal abnormality‐positive than ‐negative group (all P < 0.05). Correlation analysis showed that neither LV‐GLS nor RV‐GLS was significantly correlated with gestational age in the fetal abnormality‐negative group (all P > 0.05), whereas left ventricular GLSendo, GLSmid, and GLSepi were negatively correlated with gestational age in the fetal abnormality‐positive group (r = −.39 to −.44, all P < 0.05). Repeatability testing showed that the inter‐observer and intra‐observer intra‐class correlation coefficients for LV‐GLS and RV‐GLS in each myocardial layer were >.75 (all P < 0.001). Conclusions: As a new speckle tracking echocardiography tool, aCMQ has feasibility and repeatability in evaluating myocardial deformation of the fetal ventricle. This technique might provide helpful information on ventricular myocardial deformation in fetal hearts with abnormal structure or rhythm for clinical guidance in pregnancy.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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