IAEA/WHO GUIDELINE ON GOOD MANUFACTURING PRACTICES FOR INVESTIGATIONAL RADIOPHARMACEUTICAL PRODUCTS.

Background In view of a rapidly expanding field of molecular imaging and targeted radiopharmaceutical therapy, combined with the absence of a dedicated guidance specific to the manufacture of investigational radiopharmaceuticals used in both early and late clinical trials, the World Health Organizat...

Descripción completa

Detalles Bibliográficos
Publicado en:WHO Drug Information Vol. 35; no. 3; pp. 612 - 637
Formato: glossary Journal Article
Publicado: World Health Organization 2021
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=153891537&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 153891537
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10109609
        6FV
      jtl: WHO Drug Information
      issn: 10109609
      maglogo: N
    pubinfo:
      dt: 2021
      vid: 35
      iid: 3
      pid: 437
      pub: World Health Organization
    artinfo:
      ui:
        153891537
        153891537
        153891537
        153891537
      ppf: 612
      ppct: 25
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: IAEA/WHO GUIDELINE ON GOOD MANUFACTURING PRACTICES FOR INVESTIGATIONAL RADIOPHARMACEUTICAL PRODUCTS.
      aug:
      sug:
        subj:
          World Health Organization
          Drugs, Investigational Standards
          Practice Guidelines
          Radiopharmaceuticals Standards
          Drug Compounding Standards
          Manufacturing Industry
          Clinical Trials
          Quality Assurance
          Documentation
          Drug Labeling
          Product Development
      ab: Background In view of a rapidly expanding field of molecular imaging and targeted radiopharmaceutical therapy, combined with the absence of a dedicated guidance specific to the manufacture of investigational radiopharmaceuticals used in both early and late clinical trials, the World Health Organization (WHO), in partnership with the International Atomic Energy Agency (IAEA), has raised the urgency for the generation of a new IAEA/WHO guideline on good manufacturing practices for investigational radiopharmaceutical products . The objective of this guideline is to meet current expectations and trends in good manufacturing practices (GMP) specific to investigational radiopharmaceuticals used in clinical trials (i.e. Phase I, Phase II and Phase III trials) and to harmonize the text with the principles from other related international guidelines. This text was developed in alignment with the Good manufacturing practices; supplementary guidelines for the manufacture of investigational pharmaceutical products for clinical trials in humans (1).
      pubtype: Academic Journal
      doctype:
        glossary
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N