A Rapid Pharmacogenomic Assay to Detect Polymorphisms and Guide Isoniazid Dosing for Tuberculosis Treatment.
Rationale: Standardized dosing of antitubercular drugs contributes to a substantial incidence of toxicities, inadequate treatment response, and relapse, in part due to variable drug concentrations achieved. SNPs in the NAT2 (N-acetyltransferase-2) gene explain the majority of interindividual pharmac...
| Publicado en: | American Journal of Respiratory & Critical Care Medicine Vol. 204; no. 11; pp. 1317 - 1327 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
12/1/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |