Consensus-driven conceptual development of a standardized whole body-MRI scoring system for assessment of disease activity in juvenile idiopathic arthritis: MRI in JIA OMERACT working group.

Whole body-MRI is helpful in directing diagnostic and treatment approaches, and as a research outcome measure. We describe our initial consensus-driven phase towards developing a whole body-MRI scoring system for juvenile idiopathic arthritis. An iterative approach using three rounds of anonymous De...

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Published in:Seminars in Arthritis & Rheumatism Vol. 51; no. 6; pp. 1350 - 1360
Main Authors: Panwar, Jyoti, Tolend, Mirkamal, Redd, Bernadette, Srinivasalu, Hemalatha, Colbert, Robert A., Akikusa, Jonathan, Appenzeller, Simone, Carrino, John A., Herregods, Nele, Jans, Lennart, Highmore, Kerri, von Kalle, Thekla, Kirkhus, Eva, Rumsey, Dax G., Jaremko, Jacob L., Clemente, Inarejos Emilio J., van Rossum, Marion A., Stimec, Jennifer, Tse, Shirley M., Twilt, Marinka
Format: research Journal Article
Published: W B Saunders Dec2021
Online Access:View this record in EBSCOhost
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      dt: Dec2021
      vid: 51
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      pub: W B Saunders
      place: Philadelphia, Pennsylvania
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        154084330
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        154084330
        10.1016/j.semarthrit.2021.07.017
        154084330
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        atl: Consensus-driven conceptual development of a standardized whole body-MRI scoring system for assessment of disease activity in juvenile idiopathic arthritis: MRI in JIA OMERACT working group.
      aug:
        au:
          Panwar, Jyoti
          Tolend, Mirkamal
          Redd, Bernadette
          Srinivasalu, Hemalatha
          Colbert, Robert A.
          Akikusa, Jonathan
          Appenzeller, Simone
          Carrino, John A.
          Herregods, Nele
          Jans, Lennart
          Highmore, Kerri
          von Kalle, Thekla
          Kirkhus, Eva
          Rumsey, Dax G.
          Jaremko, Jacob L.
          Clemente, Inarejos Emilio J.
          van Rossum, Marion A.
          Stimec, Jennifer
          Tse, Shirley M.
          Twilt, Marinka
        affil: Department of Radiology, Christian Medical College, Vellore, India
      sug:
        subj:
          Arthritis Diagnosis
          Magnetic Resonance Imaging Standards
          Disease Attributes Diagnosis
          Systems Development
          Consensus
          Human
          Delphi Technique
          Questionnaires
          Pediatric Care
          Expert Clinicians
      ab: Whole body-MRI is helpful in directing diagnostic and treatment approaches, and as a research outcome measure. We describe our initial consensus-driven phase towards developing a whole body-MRI scoring system for juvenile idiopathic arthritis. An iterative approach using three rounds of anonymous Delphi surveys followed by a consensus meeting was used to draft the structure of the whole body-MRI scoring system, including the relevant anatomic joints and entheses for assessment, diagnostic item selection, definition and grading, and selection of appropriate MRI planes and sequences. The surveys were completed independently by an international expert group consisting of pediatric radiologists and rheumatologists. Twenty-two experts participated in at least one of three rounds of Delphi surveys and a concluding consensus meeting. A first iteration scoring system was developed which ultimately included the assessment of 100 peripheral, 23 chest, and 76 axial joints, and 64 entheses, with 2–4 diagnostic items graded in each of the items, using binary (presence/absence) and 2-3-level ordinal scores. Recommendations on anatomic MRI planes and sequences were specified as the minimally necessary imaging protocol for the scoring system. A novel whole body-MRI scoring system for juvenile idiopathic arthritis was developed by consensus among members of MRI in JIA OMERACT working group. Further iterative refinements, reliability testing, and responsiveness are warranted in upcoming studies. [Display omitted]
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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