Ultra-Low-Dose Spectral CT Based on a Multi-level Wavelet Convolutional Neural Network.

Spectral computed tomography (CT) based on a photon-counting detector (PCD) is a promising technique with the potential to improve lesion detection, tissue characterization, and material decomposition. PCD-based scanners have several technical issues including operation in the step-and-scan mode and...

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Published in:Journal of Digital Imaging Vol. 34; no. 6; pp. 1359 - 1376
Main Authors: Lee, Minjae, Kim, Hyemi, Cho, Hyo-Min, Kim, Hee-Joung
Format: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Published: Springer Nature Dec2021
Online Access:View this record in EBSCOhost
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      dt: Dec2021
      vid: 34
      iid: 6
      pid: 237
      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-021-00467-w
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        atl: Ultra-Low-Dose Spectral CT Based on a Multi-level Wavelet Convolutional Neural Network.
      aug:
        au:
          Lee, Minjae
          Kim, Hyemi
          Cho, Hyo-Min
          Kim, Hee-Joung
        affil: Department of Radiation Convergence Engineering, Yonsei University, 1 Yonseidae-gil, 26493, Wonju, Republic of Korea
      sug:
        subj:
          Neural Networks (Computer)
          Tomography, X-Ray Computed Methods
          Hyperspectral Imaging Methods
          Human
          Tomography, X-Ray Computed Evaluation
          Comparative Studies
          Simulations
          Radiographic Image Enhancement
      ab: Spectral computed tomography (CT) based on a photon-counting detector (PCD) is a promising technique with the potential to improve lesion detection, tissue characterization, and material decomposition. PCD-based scanners have several technical issues including operation in the step-and-scan mode and long data acquisition time. One straightforward solution to these issues is to reduce the number of projection views. However, if the projection data are under-sampled or noisy, it would be challenging to produce a correct solution without precise prior information. Recently, deep-learning approaches have demonstrated impressive performance for under-sampled CT reconstruction. In this work, the authors present a multilevel wavelet convolutional neural network (MWCNN) to address the limitations of PCD-based scanners. Data properties of the proposed method in under-sampled spectral CT are analyzed with respect to the proposed deep-running-network-based image reconstruction using two measures: sampling density and data incoherence. This work presents the proposed method and four different methods to restore sparse sampling. We investigate and compare these methods through a simulation and real experiments. In addition, data properties are quantitatively analyzed and compared for the effect of sparse sampling on the image quality. Our results indicate that both sampling density and data incoherence affect the image quality in the studied methods. Among the different methods, the proposed MWCNN shows promising results. Our method shows the highest performance in terms of various evaluation parameters such as the structural similarity, root mean square error, and resolution. Based on the results of imaging and quantitative evaluation, this study confirms that the proposed deep-running network structure shows excellent image reconstruction in sparse-view PCD-based CT. These results demonstrate the feasibility of sparse-view PCD-based CT using the MWCNN. The advantage of sparse view CT is that it can significantly reduce the radiation dose and obtain images with several energy bands by fusing PCDs. These results indicate that the MWCNN possesses great potential for sparse-view PCD-based CT.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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