Comparative Utility of Transient and 2D Shear Wave Elastography for the Assessment of Liver Fibrosis in Clinical Practice.

The aim of the study was to investigate the feasibility and correlation of liver stiffness measurements (LSM) between 2D-shear wave elastography (2D-SWE) and transient elastography (TE) in patients with chronic liver disease. Over 4 months, 421 patients with chronic liver disease of any cause underw...

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Publicado en:Journal of Digital Imaging Vol. 34; no. 6; pp. 1342 - 1349
Autores principales: Karagiannakis, Dimitrios S., Voulgaris, Theodoros, Angelopoulos, Theodoros, Ioannidou, Panagiota, Cholongitas, Evangelos, Vlachogiannakos, Jiannis, Papatheodoridis, George V.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-021-00521-7
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        atl: Comparative Utility of Transient and 2D Shear Wave Elastography for the Assessment of Liver Fibrosis in Clinical Practice.
      aug:
        au:
          Karagiannakis, Dimitrios S.
          Voulgaris, Theodoros
          Angelopoulos, Theodoros
          Ioannidou, Panagiota
          Cholongitas, Evangelos
          Vlachogiannakos, Jiannis
          Papatheodoridis, George V.
        affil: Academic Department of Gastroenterology, Medical School of National &, Laiko General Hospital, Kapodistrian University of Athens, Athens, Greece
      sug:
        subj:
          Liver Cirrhosis Ultrasonography
          Liver Physiopathology
          Ultrasonography Methods
          Chronic Disease
          Predictive Value of Tests
          Sensitivity and Specificity
          Human
          Comparative Studies
          Liver Ultrasonography
          kappa Statistic
          Obesity
          Waist Circumference
          Prospective Studies
          Descriptive Statistics
          Adult
          Middle Age
          Aged
          Female
          Male
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: The aim of the study was to investigate the feasibility and correlation of liver stiffness measurements (LSM) between 2D-shear wave elastography (2D-SWE) and transient elastography (TE) in patients with chronic liver disease. Over 4 months, 421 patients with chronic liver disease of any cause underwent LSM by 2D-SWE and TE (M and/or XL probe) and controlled attenuation parameter at the same visit. LSM was not feasible by TE in 16 (3.8%) and by 2D-SWE in 17 (4.0%) patients. Median LSM were 8.9 and 8.7 kPa with TE and 2D-SWE, respectively, having a strong correlation (r = 0.774, p < 0.001) in the total cohort and in any cause of liver disease (r = 0.747–0.806, p < 0.001). There was a strong agreement on diagnosis of severe fibrosis (k-statistic: 0.841, p < 0.001) or cirrhosis (k-statistic: 0.823, p < 0.001). Both methods had increased failure rates in patients with obesity and/or increased waist circumference. Among 104 obese patients, TE was more feasible than 2D-SWE (92.3% vs 85.6%, p < 0.001]. LSM by 2D-SWE are strongly correlated to LSM by TE independently of the etiology of chronic liver disease, stage of fibrosis, degree of liver steatosis, and patients' characteristics. TE with the XL probe may be superior in a minority of obese patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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