Reducing False-Positive Biopsies using Deep Neural Networks that Utilize both Local and Global Image Context of Screening Mammograms.

Breast cancer is the most common cancer in women, and hundreds of thousands of unnecessary biopsies are done around the world at a tremendous cost. It is crucial to reduce the rate of biopsies that turn out to be benign tissue. In this study, we build deep neural networks (DNNs) to classify biopsied...

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Publicado en:Journal of Digital Imaging Vol. 34; no. 6; pp. 1414 - 1424
Autores principales: Wu, Nan, Huang, Zhe, Shen, Yiqiu, Park, Jungkyu, Phang, Jason, Makino, Taro, Gene Kim, S., Cho, Kyunghyun, Heacock, Laura, Moy, Linda, Geras, Krzysztof J.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Dec2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2021
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      pub: Springer Nature
      place: New York, New York
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        atl: Reducing False-Positive Biopsies using Deep Neural Networks that Utilize both Local and Global Image Context of Screening Mammograms.
      aug:
        au:
          Wu, Nan
          Huang, Zhe
          Shen, Yiqiu
          Park, Jungkyu
          Phang, Jason
          Makino, Taro
          Gene Kim, S.
          Cho, Kyunghyun
          Heacock, Laura
          Moy, Linda
          Geras, Krzysztof J.
        affil: Center for Data Science, New York University, New York City, USA
      sug:
        subj:
          False Positive Results
          Neural Networks (Computer)
          Biopsy
          Mammography
          Breast Neoplasms Radiography
          Cancer Screening
          Human
          Radiologists
          Image Processing, Computer Assisted
          Deep Learning
          Breast Neoplasms Classification
      ab: Breast cancer is the most common cancer in women, and hundreds of thousands of unnecessary biopsies are done around the world at a tremendous cost. It is crucial to reduce the rate of biopsies that turn out to be benign tissue. In this study, we build deep neural networks (DNNs) to classify biopsied lesions as being either malignant or benign, with the goal of using these networks as second readers serving radiologists to further reduce the number of false-positive findings. We enhance the performance of DNNs that are trained to learn from small image patches by integrating global context provided in the form of saliency maps learned from the entire image into their reasoning, similar to how radiologists consider global context when evaluating areas of interest. Our experiments are conducted on a dataset of 229,426 screening mammography examinations from 141,473 patients. We achieve an AUC of 0.8 on a test set consisting of 464 benign and 136 malignant lesions.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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