Effects of Citric Acid in Lemon Water on the Human Intestinal Microbiota: A Comparison between Pre-Meal Intake of Water and Lemon Water.

Objective: The consumption of citric acid, contained in lemon juice, may effectively improve indigestion and maintain an optimal intestinal environment because it promotes gastric acid function. Materials and Methods: In the present study, we recruited healthy male university students and randomized...

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Publicado en:International Medical Journal Vol. 28; no. 6; pp. 625 - 629
Autores principales: Tadayuki Iida, Sari Ishigami, Masafumi Kunishige, Satona Sasagawa, Hiromi Ikeda, Satomi Aoi, Toshihide Harada
Formato: research tables/charts Journal Article
Publicado: Japan International Cultural Exchange Foundation Dec2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2021
      vid: 28
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      pub: Japan International Cultural Exchange Foundation
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        atl: Effects of Citric Acid in Lemon Water on the Human Intestinal Microbiota: A Comparison between Pre-Meal Intake of Water and Lemon Water.
      aug:
        au:
          Tadayuki Iida
          Sari Ishigami
          Masafumi Kunishige
          Satona Sasagawa
          Hiromi Ikeda
          Satomi Aoi
          Toshihide Harada
        affil: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Hiroshima 723-0053, Japan
      sug:
        subj:
          Citrates Pharmacodynamics
          Lemon Therapeutic Use
          Gut Microbiota Drug Effects
          Food Intake
          Water
          Gastric Acid
          Comparative Studies
          Random Assignment
          Students, College
          Human
          Male
          Young Adult
          Time Factors
          Feces Analysis
          Sequence Analysis Methods
          Bacteria Classification
          Nomenclature
          Gastrointestinal Motility
          Digestion
          Male
      ab: Objective: The consumption of citric acid, contained in lemon juice, may effectively improve indigestion and maintain an optimal intestinal environment because it promotes gastric acid function. Materials and Methods: In the present study, we recruited healthy male university students and randomized them into two groups that drank 300 cc of water or lemon water prior to meals for 4 weeks. Stool samples were collected before and after the test period, and the intestinal microbiota was analyzed using next generation sequencing. Bacterial species were identified based on taxonomic classification and binomial nomenclature, and were categorized at the genus level. Bacterial species with a relative abundance rate higher than 0.01% in the water- and lemon water-drinking groups were identified, and changes in the amounts of these bacteria were examined. Results and Conclusion: The results obtained revealed a significant change in the amount of Bilophila, and slight changes in the amounts of Adlercreutzia, Haemophilus, Megamonas, and Roseburia. Therefore, the pre-meal intake of lemon water appeared to promoted peristalsis and digestion, which changed the intestinal microbiota.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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