Cigarette smoking and mammographic breast density among Polish women.
Objectives: High mammographic breast density (MBD) is one of the strongest breast cancer risk factors. The results of some epidemiological studies suggest that one of the lifestyle factors likely altering breast density is cigarette smoking. The aim of this study was to assess the association betwee...
| Publicado en: | International Journal of Occupational Medicine & Environmental Health Vol. 34; no. 6; pp. 805 - 816 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Nofer Institute of Occupational Medicine
2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=154113707&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 154113707 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 12321087 E5J jtl: International Journal of Occupational Medicine & Environmental Health issn: 12321087 maglogo: N pubinfo: dt: 2021 vid: 34 iid: 6 pid: 28640 pub: Nofer Institute of Occupational Medicine artinfo: ui: 154113707 154113707 NLM34524273 10.13075/ijomeh.1896.01832 NLM34524273 154113707 ppf: 805 ppct: 11 formats: tig: atl: Cigarette smoking and mammographic breast density among Polish women. aug: au: PEPŁOŃSKA, BEATA KAŁUŻNY, PAWEŁ Pepłońska, Beata Kalużny, Pawel affil: Department of Environmental Epidemiology, Epidemiology Unit, Nofer Institute of Occupational Medicine, Łódź, Poland sug: subj: Breast Neoplasms Breast Neoplasms Epidemiology Poland Cross Sectional Studies Female Mammography Early Detection of Cancer Female ab: Objectives: High mammographic breast density (MBD) is one of the strongest breast cancer risk factors. The results of some epidemiological studies suggest that one of the lifestyle factors likely altering breast density is cigarette smoking. The aim of this study was to assess the association between active smoking, considering in detail the duration and intensity of smoking, and MBD among Polish women.Material and Methods: A cross-sectional study included 467 women aged 40-60 years who underwent screening mammography in Łódź, Poland. Volumetric mammographic density, fibroglandular tissue volume and non-fibroglandular tissue volume were determined based on the analysis of mammographic image (in the "for processing" format) using Volpara Imaging Software. Current and lifetime intensity of cigarette smoking was assessed based on the data from interviews. Linear and logistic regressions were fitted with estimated MBD parameters as the outcomes, and life-long smoking duration and intensity as the determinants, adjusted for major confounders.Results: The former smokers had a significantly lower volumetric mammographic density compared to the non-smokers in the crude analysis (p = 0.022). However, the associations became insignificant after adjustments for important confounding factors. The analyses adjusted for important confounders revealed an inverse statistically significant association between the number of pack-years and volumetric mammographic density among the current smokers (p = 0.048).Conclusions: The observed result is consistent with the majority of previous studies that analyzed the associations between mammographic density and life-long smoking duration. Int J Occup Med Environ Health. 2021;34(6):805-15. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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