| Sumario: | Traumatic brain injury leads to mortality and disability with consequences for the poor quality of life of people. Little study regarding the quality of life of people with traumatic brain injury in Bangladesh exists. This cross-sectional study aims to examine the quality of life and its influencing factors among people with moderate to severe traumatic brain injury. The participants were 249 people with moderate to severe traumatic brain injury, and their caregivers recruited from three public hospitals in Bangladesh. Data were collected through questionnaires including socio-demographic, the Injury Related Illness and Injury Severity Score questionnaire, the Charlson Comorbidity Index, the Modified Barthel Index, the Patients Health Questionnaire-9, the MOS-Social Support Survey, the Quality of Life after Brain Injury (QOLIBRI), the caregiver socio-demographic, and the Caregiver Preparedness Scale. Data were analyzed using descriptive statistics, Pearson's correlation test, and stepwise multiple regression model. Results showed that majority of the people reported a poor quality of life. Stepwise multiple regression analysis revealed that social support, caregiver preparedness, depression, and income, were significant factors and could explain 37% variance of quality of life. To improve the quality of life among people with traumatic brain injury, nurses should seek significant resources to support them, perform emotional support to prevent depression and prepare their caregivers with knowledge and proper skills for patients' care. Eventually, they can have healthy transition and obtain desirable health outcomes with good quality of life.
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