Metastatic embryonal rhabdomyosarcoma of the breast: A case report and literature review.

Rhabdomyosarcoma (RMS) is a common malignancy in children, but embryonal rhabdomyosarcoma (ERMS) deposits rarely occur in the breast in adults. Therefore, little is known about magnetic resonance imaging (MRI) features of breast metastases from RMS, especially the embryonal type. We reported a case...

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Publicado en:Breast Journal Vol. 27; no. 12; pp. 890 - 895
Autores principales: Ma, Xuejin, Chen, Xiaoxi, Jiang, Guoyuan, Jiang, Lin, Li, Tingchao, Wei, Ling, Li, Shiguang
Formato: case study diagnostic images pictorial tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2021
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      pub: Wiley-Blackwell
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        10.1111/tbj.14284
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        atl: Metastatic embryonal rhabdomyosarcoma of the breast: A case report and literature review.
      aug:
        au:
          Ma, Xuejin
          Chen, Xiaoxi
          Jiang, Guoyuan
          Jiang, Lin
          Li, Tingchao
          Wei, Ling
          Li, Shiguang
        affil: Department of Radiology, The First People's Hospital of Zunyi, The Third Affiliated Hospital of Zunyi Medical University, Zunyi, China
      sug:
        subj:
          Rhabdomyosarcoma Complications
          Neoplasms, Germ Cell and Embryonal Complications
          Breast Neoplasms Risk Factors
          Neoplasm Metastasis Risk Factors
          Magnetic Resonance Imaging
          Adult
          Female
          Necrosis Complications
          Breast Ultrasonography
          Edema Complications
          Adult: 19-44 years
          Female
      ab: Rhabdomyosarcoma (RMS) is a common malignancy in children, but embryonal rhabdomyosarcoma (ERMS) deposits rarely occur in the breast in adults. Therefore, little is known about magnetic resonance imaging (MRI) features of breast metastases from RMS, especially the embryonal type. We reported a case of a 22‐year‐old woman who was diagnosed with ERMS at left foot 2 years ago and accepted operation and chemotherapy. She was confirmed to have breast metastases from the left foot. Successive imaging examinations were performed 3 months apart. Breast ultrasound indicated a benign lesion, and further examination did not reveal any bone metastases. However, predominant restricted diffusion and rim contrast enhancement on MRI combined with the patient's medical history suggested a malignancy of BI‐RADS 5. After 3 months, breast ultrasound revealed masses detected last time became larger and lobulated. In addition, internal heterogeneous intensity and rim contrast enhancement with restricted diffusion were revealed on MRI. We speculated that typical MRI findings of breast metastases from RMS may include iso‐ to hypointensity on T1WI, heterogeneous hyperintensity on T2WI, and circular enhancement with restricted diffusion. Moreover, mild peritumoral edema, rapid expansion of necrosis, and ascending time‐intensity curve detected on MRI may be features of the ERMS type.
      pubtype: Academic Journal
      doctype:
        case study
        diagnostic images
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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