Mobility and Depressive Symptoms in Persons With Mild Cognitive Impairment and Alzheimer Dementia.
Supplemental Digital Content is Available in the Text. Background and Purpose: Persons with mild cognitive impairment (MCI) and Alzheimer dementia (AD) often experience gait and balance disturbances and depressive symptoms alongside their cognitive impairment. The aim of this study was to explore th...
| Publicado en: | Journal of Neurologic Physical Therapy Vol. 43; no. 1; pp. 11 - 18 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jan2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=154221077&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 154221077 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15570576 1FUT jtl: Journal of Neurologic Physical Therapy issn: 15570576 maglogo: N pubinfo: dt: Jan2022 vid: 43 iid: 1 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 154221077 154221077 154221077 10.1097/NPT.0000000000000378 154221077 ppf: 11 ppct: 7 formats: tig: atl: Mobility and Depressive Symptoms in Persons With Mild Cognitive Impairment and Alzheimer Dementia. aug: au: Flugon, Susannah Julie Jøranson, Nina Tangen, Gro Gujord affil: Municipality of Oslo, Oslo, Norway (S.J.F.) sug: subj: Physical Mobility Walking Speed Balance, Postural Task Performance and Analysis Depression Symptoms Depression Risk Factors Alzheimer's Disease Community Living Risk Assessment Mild Cognitive Impairment Psychosocial Factors Human Norway Academic Medical Centers Clinical Assessment Tools Psychological Tests Questionnaires Cross Sectional Studies International Classification of Diseases T-Tests Chi Square Test Fisher's Exact Test Multiple Regression Data Analysis Software Female Male Middle Age Aged Aged, 80 and Over Mann-Whitney U Test Descriptive Statistics Confidence Intervals Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: Supplemental Digital Content is Available in the Text. Background and Purpose: Persons with mild cognitive impairment (MCI) and Alzheimer dementia (AD) often experience gait and balance disturbances and depressive symptoms alongside their cognitive impairment. The aim of this study was to explore the relationship between mobility and depressive symptoms in community-dwelling persons with MCI and mild to moderate AD. Methods: Ninety-nine participants with MCI and AD from the memory clinic at Oslo University Hospital, Ullevål, Norway, were included. The Balance Evaluation Systems Test (BESTest), 10-m walk test regular (gait speed), and dual task (naming animals, dual-task cost in percent) were used to assess mobility. The Cornell Scale for Depression in Dementia, with validated cut-off 5/6 points, was used to assess presence of depressive symptoms. Multiple regression analysis was used to explore the relationship between mobility (3 separate models) and depressive symptoms, controlled for demographic factors, comorbidity, and Mini-Mental State Examination. Results: One-third of the participants had depressive symptoms, mean (SD) gait speed was 1.09 (0.3) m/s, and median (interquartile range) BESTest percent score was 81.5 (17.6). No statistically significant associations were found between depression and BESTest, gait speed or dual-task cost, neither in the simple models (P = 0.15-0.85), nor in the 3 multivariate models (P = 0.57-0.69). Discussion and Conclusions: In this study, we found no associations between mobility and depressive symptoms in persons with MCI and AD recruited at a memory clinic. Few participants had major symptoms of depression, which may have influenced the results. Longitudinal studies are needed to explore the long-time associations between mobility and depression. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A366). pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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