Unraveling the Cognitive-Motor Interaction in Individuals With Amnestic Mild Cognitive Impairment.

Supplemental Digital Content is Available in the Text. Purpose: This study aimed to determine whether increasing the contribution of executive functions worsens dual-task performance in individuals with amnestic mild cognitive impairment (aMCI). Methods: Fourteen individuals with aMCI (mean [SD]: 74...

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Publicado en:Journal of Neurologic Physical Therapy Vol. 43; no. 1; pp. 18 - 26
Autores principales: Gaillardin, Florence, Bier, Jean-Christophe, De Breucker, Sandra, Baudry, Stéphane
Formato: research tables/charts Journal Article
Publicado: Lippincott Williams & Wilkins Jan2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2022
      vid: 43
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      pub: Lippincott Williams & Wilkins
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        10.1097/NPT.0000000000000386
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        atl: Unraveling the Cognitive-Motor Interaction in Individuals With Amnestic Mild Cognitive Impairment.
      aug:
        au:
          Gaillardin, Florence
          Bier, Jean-Christophe
          De Breucker, Sandra
          Baudry, Stéphane
        affil: Laboratory of Applied Biology and Research Unit in Applied Neurophysiology (LABNeuro), Faculty for Motor Sciences, Université Libre de Bruxelles (ULB), Brussels, Belgium (F.G., S.B.)
      sug:
        subj:
          Amnesia
          Mild Cognitive Impairment
          Executive Function
          Task Performance and Analysis
          Human
          Aged
          Descriptive Statistics
          Locomotion
          Stair Climbing
          Male
          Female
          T-Tests
          Analysis of Variance
          Post Hoc Analysis
          Funding Source
          Aged: 65+ years
          Male
          Female
      ab: Supplemental Digital Content is Available in the Text. Purpose: This study aimed to determine whether increasing the contribution of executive functions worsens dual-task performance in individuals with amnestic mild cognitive impairment (aMCI). Methods: Fourteen individuals with aMCI (mean [SD]: 74 [4] years) and 19 control adults (71 [5] years) recalled a list of letters in the order of presentation (SPAN-O) or in alphabetic order (SPAN-A) while ascending or descending a 3-step staircase. Dual-task cost (DTC) represented the average decrement of motor and cognitive performances during dual tasks, with greater DTC indicating worse performance. Results: SPAN-A (P < 0.001) and stair descent (P = 0.023) increased the DTC in both groups compared with SPAN-O and stair ascent. Furthermore, individuals with aMCI had a greater DTC (93.4 [41.2]%) than the control group (48.3 [27.9]%) for SPAN-A (P < 0.001). Dual-task cost was also greater in descent (76.6 [42.1]%) than ascent (64.0 [34.5]%) in individuals with aMCI (P = 0.024) but not in the control group (P = 0.99). Significant negative partial correlations (β < −0.39; P < 0.05) were found between Montreal Cognitive Assessment score and DTC, while controlling for age and physical function. Discussion and Conclusions: A greater DTC in individuals with aMCI when the cognitive task requires working memory (SPAN-A) or during complex locomotor task (descent) suggests that aMCI impedes the capacity to perform 2 tasks simultaneously when higher-order cognitive processes are challenged. Furthermore, a greater DTC in our dual-task situations appears to reflect cognitive decline, as assessed by the Montreal Cognitive Assessment score. Overall, this study indicates that increasing the contribution of executive functions worsens the cognitive-motor interaction in individuals with aMCI. Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1 available at: http://links.lww.com/JNPT/A375).
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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