BRCA1/2 Mutation Types Do Not Affect Prognosis in Ovarian Cancer Patients.

Background: High grade serous ovarian carcinoma (HGSOC) is the most lethal type of epithelial ovarian cancer, with a prevalence of germline BRCA1/2 mutations as high as 20%. Our objective is to determine whether the location of mutations in the different domains of the BRCA1/2 genes affects the clin...

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Publicado en:	Current Oncology Vol. 28; no. 6; pp. 4446 - 4457
Autores principales:	Liontos, Michalis, Zografos, Eleni, Zoumpourlis, Panagiotis, Andrikopoulou, Angeliki, Svarna, Anna, Fiste, Oraianthi, Kunadis, Elena, Papatheodoridi, Alkistis Maria, Kaparelou, Maria, Koutsoukos, Konstantinos, Thomakos, Nikoloas, Haidopoulos, Dimitrios, Rodolakis, Alexandros, Dimopoulos, Meletios-Athanasios, Zagouri, Flora
Formato:	Journal Article
Publicado:	MDPI Dec2021
Acceso en línea:	Ver este registro en EBSCOhost