Treatment Algorithm in Cancer-Associated Thrombosis: Updated Canadian Expert Consensus.

Patients with cancer-associated thrombosis (CAT) are at high risk of recurrent venous thromboembolism (VTE) and major bleeding complications. Risks vary significantly between individuals based on cancer status, treatment, and other characteristics. To facilitate the evidence-based management of anti...

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Publicado en:Current Oncology Vol. 28; no. 6; pp. 5434 - 5452
Autores principales: Carrier, Marc, Blais, Normand, Crowther, Mark, Kavan, Petr, Le Gal, Grégoire, Moodley, Otto, Shivakumar, Sudeep, Suryanarayan, Deepa, Tagalakis, Vicky, Cynthia Wu, Lee, Agnes Y. Y.
Formato: Journal Article
Publicado: MDPI Dec2021
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Treatment Algorithm in Cancer-Associated Thrombosis: Updated Canadian Expert Consensus.
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        au:
          Carrier, Marc
          Blais, Normand
          Crowther, Mark
          Kavan, Petr
          Le Gal, Grégoire
          Moodley, Otto
          Shivakumar, Sudeep
          Suryanarayan, Deepa
          Tagalakis, Vicky
          Cynthia Wu
          Lee, Agnes Y. Y.
        affil: Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa Ottawa, ON K1H 8L6, Canada
      sug:
      ab: Patients with cancer-associated thrombosis (CAT) are at high risk of recurrent venous thromboembolism (VTE) and major bleeding complications. Risks vary significantly between individuals based on cancer status, treatment, and other characteristics. To facilitate the evidence-based management of anticoagulant therapy in this patient population, a committee of 11 Canadian clinical experts updated a consensus-based algorithm for the acute and extended treatment of symptomatic and incidental CAT that was developed in 2018. Following a systematic review of the literature, updates to the algorithm were discussed during an online teleconference, and the algorithm was subsequently refined based on feedback from committee members. Clinicians using this treatment algorithm should consider bleeding risk, type of cancer, and drug-drug interactions, as well as patient and clinician preferences, in tailoring anticoagulation for patients with CAT. Anticoagulant therapy should be adapted as the patient's cancer status and management change over time.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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