Andrographolide Induces Apoptosis and Cell Cycle Arrest through Inhibition of Aberrant Hedgehog Signaling Pathway in Colon Cancer Cells.

Background Hedgehog signaling pathway (Hh) is abnormally stimulated in colon cancer. Evidence suggests the therapeutic effectiveness of andrographolide against several cancers. This study attempts to delineate the effect of andrographolide on Hh signaling pathway in colon cancer HCT-116 cells. Metho...

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Bibliographic Details
Published in:Nutrition & Cancer Vol. 73; no. 11/12; pp. 2428 - 2447
Main Authors: Khan, Imran, Mahfooz, Sadaf, Faisal, Mohammad, Alatar, Abdulrahman A., Ansari, Irfan A.
Format: pictorial research tables/charts Journal Article
Published: Taylor & Francis Ltd 2021
Online Access:View this record in EBSCOhost