Two-way comparison of brain perfusion image processing software for patients with acute ischemic strokes in real-world.
Purpose: Perfusion imaging generates multimaps of ischemic tissues and is a proven decision-making tool in patients with acute ischemic stroke. However, the reliability of perfusion post-processing outcomes has been debated, given disparate results of various software applications, especially for pa...
| Publicado en: | Neuroradiology Vol. 64; no. 1; pp. 161 - 170 |
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| Autores principales: | , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jan2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=154457838&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 154457838 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283940 NYZ jtl: Neuroradiology issn: 00283940 maglogo: N pubinfo: dt: Jan2022 vid: 64 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 154457838 151660301 154457838 154457838 10.1007/s00234-021-02771-2 154457838 ppf: 161 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Two-way comparison of brain perfusion image processing software for patients with acute ischemic strokes in real-world. aug: au: Cai, Heng Fan, Shengyu Bian, Yueyan Yang, Qi Long, Zhenhai Chen, Liangyu Tang, Wei Zhang, Nan Zhen, Yongyu Li, Zhiqing affil: Department of Neurosurgery, Shengjing Hospital of China Medical University, 110004, Shenyang, People's Republic of China sug: subj: Brain Blood Supply Perfusion Imaging Methods Image Processing, Computer Assisted Software Ischemic Stroke Pathology Cerebral Blood Volume Evaluation Human Stroke Patients Comparative Studies Netherlands Tomography, X-Ray Computed Intraclass Correlation Coefficient Sensitivity and Specificity Evaluation Descriptive Statistics Confidence Intervals Retrospective Design Ischemic Stroke Radiography Brain Radiography ab: Purpose: Perfusion imaging generates multimaps of ischemic tissues and is a proven decision-making tool in patients with acute ischemic stroke. However, the reliability of perfusion post-processing outcomes has been debated, given disparate results of various software applications, especially for patients with small ischemic core volume. This study was undertaken to compare ischemic volume estimates determined by imSTROKE (a software with new imaging protocol) and RAPID computer applications, respectively. Methods: A total of 611 patients qualified for study, each having met inclusion and exclusion criteria of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN trial). Subjects were examined by computed tomography perfusion (CTP) imaging (n = 349) or perfusion-weighted (PWI) and diffusion-weighted (DWI) imaging (n = 262). Ischemic volumes estimated by imSTROKE and RAPID applications were then compared. We used Bland-Altman analysis and intraclass correlation coefficients (ICCs) to ascertain agreement between applications. Accuracies of estimated core infarct and penumbra volumes were tested at specific thresholds (core: 25 mL, 50 mL, and 70 mL; penumbra: 45 mL, 90 mL, and 125 mL). Results: Median core infarct volumes by imSTROKE and RAPID were 29.18 mL and 29.53 mL, respectively (ICC = 0.9880, 95% confidence interval [CI]: 0.9860–0.9898). Median penumbra volumes by imSTROKE and RAPID were 68.20 mL and 68.55 mL, respectively (ICC = 0.9885, 95% CI: 0.9865–0.9902). Conclusion: In estimating core infarct and penumbra volumes, imSTROKE and RAPID applications showed high-level agreement. For patients with small ischemic core volume, compared with RAPID, imSTROKE may have better sensitivity. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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