Increased prefrontal cortical activation during challenging walking conditions in persons with lower limb amputation – an fNIRS observational study.

Background: Lower limb amputation (LLA) alters the sensorimotor control systems. Despite the self-reports of increased attention during mobility, the interaction between mobility and cognitive control mechanisms is not fully understood. Objective: Concurrently evaluate walking performance and prefro...

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Publicado en:Physiotherapy Theory & Practice Vol. 38; no. 2; pp. 255 - 266
Autores principales: Schack, Jette, Pripp, aAre Hugo, Mirtaheri, Peyman, Steen, Harald, Güler, Evin, Gjøvaag, Terje
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Feb 022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb 022
      vid: 38
      iid: 2
      pid: 377
      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/09593985.2020.1758979
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        atl: Increased prefrontal cortical activation during challenging walking conditions in persons with lower limb amputation – an fNIRS observational study.
      aug:
        au:
          Schack, Jette
          Pripp, aAre Hugo
          Mirtaheri, Peyman
          Steen, Harald
          Güler, Evin
          Gjøvaag, Terje
        affil: Department of Occupational Therapy, Prosthetics and Orthotics, Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway
      sug:
        subj:
          Walking
          Task Performance and Analysis
          Prefrontal Cortex Physiology
          Lower Extremity Surgery
          Amputation
          Surgical Patients
          Human
          Nonexperimental Studies
          Spectroscopy, Near-Infrared
          Models, Statistical
          Comparative Studies
          Cognition Evaluation
          Attention
          Limb Prosthesis
          Gait
          Neuroradiography
          Funding Source
          Neuropsychological Tests
          Clinical Assessment Tools
          Data Analysis Software
          Descriptive Statistics
          T-Tests
          Chi Square Test
          Post Hoc Analysis
          Pearson's Correlation Coefficient
          Male
          Female
          Adult
          Middle Age
          Aged
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background: Lower limb amputation (LLA) alters the sensorimotor control systems. Despite the self-reports of increased attention during mobility, the interaction between mobility and cognitive control mechanisms is not fully understood. Objective: Concurrently evaluate walking performance and prefrontal cortical (PFC) activity in persons with and without LLA during different walking conditions. Methods: Thirty-nine persons with LLA and thirty-three able-bodied controls participated. Walking performance was evaluated using the Figure-of 8-walk-test during three conditions: 1) UW (Usual walking with self-selected walking speed); 2) WCT (walking and carrying a tray with two cups filled with water); and 3) WUT (walking on uneven terrain). PFC activity was assessed using functional near-infrared spectroscopy (fNIRS). Linear mixed models were used to detect changes between groups and between walking conditions within each group. Results: Between-group comparisons showed increased PFC activity in persons with LLA during UW and WUT, and a significant decrease in walking performance during WCT and WUT compared to controls. Within-group comparisons showed increased PFC activity during WUT compared with UW and WCT and an overall difference in walking performance between the conditions (WU > WUT > WCT) in both groups. However, the effect of walking condition on PFC activity and walking performance was not modified by group (P >.1). Conclusion: The results suggest that persons with LLA have increased attentional demands during walking but choose the same cognitive-mobility strategy during challenging walking conditions as able-bodied persons. However, the attentional demands seem to depend on the complexity of the task.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Unknown
    language: English
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