The translocator protein gene is associated with endogenous pain modulation and the balance between glutamate and γ-aminobutyric acid in fibromyalgia and healthy subjects: a multimodal neuroimaging study.

Abstract: A cerebral upregulation of the translocator protein (TSPO), a biomarker of glial activation, has been reported in fibromyalgia subjects (FMS). The TSPO binding affinity is genetically regulated by the Ala147Thr polymorphism in the TSPO gene (rs6971) and allows for a subject classification...

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Bibliographic Details
Published in:PAIN Vol. 163; no. 2; pp. 274 - 287
Main Authors: Fanton, Silvia, Sandström, Angelica, Tour, Jeanette, Kadetoff, Diana, Schalling, Martin, Jensen, Karin B., Sitnikov, Rouslan, Ellerbrock, Isabel, Kosek, Eva
Format: research Journal Article
Published: Lippincott Williams & Wilkins 2/1/2022
Online Access:View this record in EBSCOhost