Design, synthesis and biological evaluation of dual HDAC and VEGFR inhibitors as multitargeted anticancer agents.

Summary: Herein, a novel series of dual histone deacetylase (HDAC) and vascular endothelial growth factor receptor (VEGFR) inhibitors were designed, synthesized and biologically evaluated based on previously reported pazopanib-based HDAC and VEGFR dual inhibitors. Most target compounds showed signif...

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Bibliographic Details

Published in:	Investigational New Drugs Vol. 40; no. 1; pp. 10 - 21
Main Authors:	Xue, Xia, Zhang, Yingjie, Liao, Yongxiang, Sun, Deqing, Li, Lina, Liu, Ying, Wang, Yongjie, Jiang, Wen, Zhang, Jian, Luan, Yun, Zhao, Xiaogang
Format:	pictorial research tables/charts Journal Article
Published:	Springer Nature Feb2022
Online Access:	View this record in EBSCOhost