Potential applications and performance of machine learning techniques and algorithms in clinical practice: A systematic review.
Purpose: The advent of clinically adapted machine learning algorithms can solve numerous problems ranging from disease diagnosis and prognosis to therapy recommendations. This systematic review examines the performance of machine learning (ML) algorithms and evaluates the progress made to date towar...
| Publicado en: | International Journal of Medical Informatics Vol. 159 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
Mar2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=154737304&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 154737304 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13865056 JR4 jtl: International Journal of Medical Informatics issn: 13865056 maglogo: N pubinfo: dt: Mar2022 vid: 159 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 154737304 154737304 NLM34990939 10.1016/j.ijmedinf.2021.104679 NLM34990939 154737304 ppct: 1 formats: tig: atl: Potential applications and performance of machine learning techniques and algorithms in clinical practice: A systematic review. aug: au: Nwanosike, Ezekwesiri Michael Conway, Barbara R Merchant, Hamid A Hasan, Syed Shahzad affil: Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate Huddersfield HD1 3DH, West Yorkshire, United Kingdom sug: ab: Purpose: The advent of clinically adapted machine learning algorithms can solve numerous problems ranging from disease diagnosis and prognosis to therapy recommendations. This systematic review examines the performance of machine learning (ML) algorithms and evaluates the progress made to date towards their implementation in clinical practice.Methods: Systematic searching of databases (PubMed, MEDLINE, Scopus, Google Scholar, Cochrane Library and WHO Covid-19 database) to identify original articles published between January 2011 and October 2021. Studies reporting ML techniques in clinical practice involving humans and ML algorithms with a performance metric were considered.Results: Of 873 unique articles identified, 36 studies were eligible for inclusion. The XGBoost (extreme gradient boosting) algorithm showed the highest potential for clinical applications (n = 7 studies); this was followed jointly by random forest algorithm, logistic regression, and the support vector machine, respectively (n = 5 studies). Prediction of outcomes (n = 33), in particular Inflammatory diseases (n = 7) received the most attention followed by cancer and neuropsychiatric disorders (n = 5 for each) and Covid-19 (n = 4). Thirty-three out of the thirty-six included studies passed more than 50% of the selected quality assessment criteria in the TRIPOD checklist. In contrast, none of the studies could achieve an ideal overall bias rating of 'low' based on the PROBAST checklist. In contrast, only three studies showed evidence of the deployment of ML algorithm(s) in clinical practice.Conclusions: ML is potentially a reliable tool for clinical decision support. Although advocated widely in clinical practice, work is still in progress to validate clinically adapted ML algorithms. Improving quality standards, transparency, and interpretability of ML models will further lower the barriers to acceptability. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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