Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies.

Purpose: To demonstrate the feasibility and diagnostic value of high-frequency magnetic resonance elastography (MRE) for evaluation of prostatic disease in patients with lower urinary tract symptoms (LUTS). Methods: 41 patients who underwent preoperative prostate MRI and MRE with a modified driver w...

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Publicado en:Abdominal Radiology Vol. 47; no. 1; pp. 399 - 409
Autores principales: Deng, Ying, Yi, Zhuoya, Zhang, Tianhui, Hu, Bing, Zhang, Linqi, Rajlawot, Kritisha, Kuang, Sichi, He, Bingjun, Arani, Arvin, Chen, Jun, Yin, Meng, Rossman, Phillip, Glaser, Kevin J., Venkatesh, Sudhakar K., Ehman, Richard L., Wang, Jin
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Jan2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2022
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      pub: Springer Nature
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        10.1007/s00261-021-03302-6
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        atl: Magnetic resonance elastography of the prostate in patients with lower urinary tract symptoms: feasibility of the modified driver at high multi-frequencies.
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        au:
          Deng, Ying
          Yi, Zhuoya
          Zhang, Tianhui
          Hu, Bing
          Zhang, Linqi
          Rajlawot, Kritisha
          Kuang, Sichi
          He, Bingjun
          Arani, Arvin
          Chen, Jun
          Yin, Meng
          Rossman, Phillip
          Glaser, Kevin J.
          Venkatesh, Sudhakar K.
          Ehman, Richard L.
          Wang, Jin
        affil: Department of Radiology, the Third Affiliated Hospital, Sun Yat-Sen University (SYSU), No 600, Tianhe Road, 510630, Guangzhou, Guangdong, People's Republic of China
      sug:
        subj:
          Magnetic Resonance Imaging
          Prostate Radiography
          Urinary Tract Infections
          Prostatic Diseases
          Human
          Retrospective Design
          Quantitative Studies
          Qualitative Studies
          Biopsy
          Prostatectomy
          One-Way Analysis of Variance
          T-Tests
          ROC Curve
          Diagnostic Imaging
      ab: Purpose: To demonstrate the feasibility and diagnostic value of high-frequency magnetic resonance elastography (MRE) for evaluation of prostatic disease in patients with lower urinary tract symptoms (LUTS). Methods: 41 patients who underwent preoperative prostate MRI and MRE with a modified driver were enrolled retrospectively from May 2016 to September 2021. All were included in the assessment of MRE image quality, using a qualitative visual inspection and a quantitative confidence map. 35 patients (prostate cancer (PCa), n = 13; non-PCa, n = 22) undergoing prostatectomy or biopsy were evaluated for the diagnostic performance of stiffness values. The confidence values and the stiffness values were analyzed by one-way analysis of variance (ANOVA) and independent samples T test, respectively. Area under the receiver operating characteristic (AUROC) analysis was performed. Results: Through the qualitative analysis, all MRE acquisitions were successful at 60, 90, 120 and 150 Hz. The quantitative confidence values were significantly lower at 60 Hz (0.683 ± 0.055) and 90 Hz (0.762 ± 0.048) than that at 120 Hz (0.814 ± 0.049) and 150 Hz (0.840 ± 0.049), all P < 0.001. The stiffness of PCa was higher than non-PCa at 90 Hz (P = 0.008), 120 Hz (P < 0.001) and 150 Hz (P < 0.001). The AUCs were 0.773, 0.881 and 0.944, respectively. Conclusion: Prostate MRE using the modified driver is feasible at 60–150 Hz and image quality is better at higher frequencies. Prostate MRE may be useful and helpful to evaluate prostate diseases in patients with LUTS at higher frequencies; however, further study may be warranted with larger population in future.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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