Impact of including second and later cancers in cause-specific survival estimates using population-based registry data.

Background: Second or later primary cancers account for approximately 20% of incident cases in the United States. Currently, cause-specific survival (CSS) analyses exclude these cancers because the cause of death (COD) classification algorithm was available only for first cancers. The authors added...

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Publicado en:Cancer (0008543X) Vol. 128; no. 3; pp. 547 - 558
Autores principales: Forjaz, Gonçalo, Howlader, Nadia, Scoppa, Steve, Johnson, Christopher J., Mariotto, Angela B.
Formato: research Journal Article
Publicado: Wiley-Blackwell Feb2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2022
      vid: 128
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1002/cncr.33940
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        atl: Impact of including second and later cancers in cause-specific survival estimates using population-based registry data.
      aug:
        au:
          Forjaz, Gonçalo
          Howlader, Nadia
          Scoppa, Steve
          Johnson, Christopher J.
          Mariotto, Angela B.
        affil: Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville Maryland
      sug:
        subj:
          Neoplasms Pathology
          Data Collection
          United States
          Cause of Death
          Registries, Disease
          Prospective Studies
          Aged
          Human
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Impact of Events Scale
          Aged: 65+ years
      ab: Background: Second or later primary cancers account for approximately 20% of incident cases in the United States. Currently, cause-specific survival (CSS) analyses exclude these cancers because the cause of death (COD) classification algorithm was available only for first cancers. The authors added rules for later cancers to the Surveillance, Epidemiology, and End Results cause-specific death classification algorithm and evaluated CSS to include individuals with prior tumors.Methods: The authors constructed 2 cohorts: 1) the first ever primary cohort, including patients whose first cancer was diagnosed during 2000 through 2016) and 2) the earliest matching primary cohort, including patients with any cancer who matched the selection criteria irrespective of whether it was the first or a later cancer diagnosed during 2000 through 2016. The cohorts' CSS estimates were compared using follow-up through December 31, 2017. The new rules were used in the second cohort for patients whose first cancers during 2000 through 2016 were their second or later cancers.Results: Overall, there were no statistically significant differences in CSS estimates between the 2 cohorts. Estimates were similar by age, stage, race, and time since diagnosis, except for patients with leukemia and those aged 65 to 74 years (3.4 percentage point absolute difference).Conclusions: The absolute difference in CSS estimates for the first cancer ever cohort versus earliest of any cancers cohort in the study period was small for most cancer types. As the number of newly diagnosed patients with prior cancers increases, the algorithm will make CSS more inclusive and enable estimating survival for a group of patients with cancer for whom life tables are not available or life tables are available but do not capture other-cause mortality appropriately.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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