Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study.

Objectives: This study aimed to determine the prevalence of ultrasound-detected tendon abnormalities in healthy subjects (HS) across the age range.Methods: Adult HS (age 18-80 years) were recruited in 23 international Outcome Measures in Rheumatology ultrasound centres and were clinically assessed t...

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Publicado en:Annals of the Rheumatic Diseases Vol. 81; no. 2; pp. 232 - 237
Autores principales: Trickey, Jeanette, Sahbudin, Ilfita, Ammitzbøll-Danielsen, Mads, Azzolin, Irene, Borst, Carina, Bortoluzzi, Alessandra, Bruyn, George A.W., Carron, Philippe, Ciurtin, Coziana, Filippou, Georgios, Fliciński, Jacek, Fodor, Daniela, Gouze, Hélène, Gutierrez, Marwin, Hammer, Hilde Berner, Hauge, Ellen-Margrethe, Iagnocco, Annamaria, Ikeda, Kei, Karalilova, Rositsa, Keen, Helen Isobel
Formato: research Journal Article
Publicado: Elsevier B.V. Feb2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2022
      vid: 81
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      pub: Elsevier B.V.
      place: New York, New York
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        154805338
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        NLM34407928
        154805338
        10.1136/annrheumdis-2021-219931
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        154805338
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        atl: Very low prevalence of ultrasound-detected tenosynovial abnormalities in healthy subjects throughout the age range: OMERACT ultrasound minimal disease study.
      aug:
        au:
          Trickey, Jeanette
          Sahbudin, Ilfita
          Ammitzbøll-Danielsen, Mads
          Azzolin, Irene
          Borst, Carina
          Bortoluzzi, Alessandra
          Bruyn, George A.W.
          Carron, Philippe
          Ciurtin, Coziana
          Filippou, Georgios
          Fliciński, Jacek
          Fodor, Daniela
          Gouze, Hélène
          Gutierrez, Marwin
          Hammer, Hilde Berner
          Hauge, Ellen-Margrethe
          Iagnocco, Annamaria
          Ikeda, Kei
          Karalilova, Rositsa
          Keen, Helen Isobel
        affil: Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
      sug:
        subj:
          Tenosynovitis Epidemiology
          Tendons Pathology
          Tendons
          Prospective Studies
          Hypertrophy
          Human
          Prevalence
          Tenosynovitis
          Adolescence
          Middle Age
          Aged
          Male
          Young Adult
          Ultrasonography
          Hypertrophy Epidemiology
          Aged, 80 and Over
          Female
          Adult
          Research Subjects
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Funding Source
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Adult: 19-44 years
          Male
          Female
      ab: Objectives: This study aimed to determine the prevalence of ultrasound-detected tendon abnormalities in healthy subjects (HS) across the age range.Methods: Adult HS (age 18-80 years) were recruited in 23 international Outcome Measures in Rheumatology ultrasound centres and were clinically assessed to exclude inflammatory diseases or overt osteoarthritis before undergoing a bilateral ultrasound examination of digit flexors (DFs) 1-5 and extensor carpi ulnaris (ECU) tendons to detect the presence of tenosynovial hypertrophy (TSH), tenosynovial power Doppler (TPD) and tenosynovial effusion (TEF), usually considered ultrasound signs of inflammatory diseases. A comparison cohort of patients with rheumatoid arthritis (RA) was taken from the Birmingham Early Arthritis early arthritis inception cohort.Results: 939 HS and 144 patients with RA were included. The majority of HS (85%) had grade 0 for TSH, TPD and TEF in all DF and ECU tendons examined. There was a statistically significant difference in the proportion of TSH and TPD involvement between HS and subjects with RA (HS vs RA p<0.001). In HS, there was no difference in the presence of ultrasound abnormalities between age groups.Conclusions: Ultrasound-detected TSH and TPD abnormalities are rare in HS and can be regarded as markers of active inflammatory disease, especially in newly presenting RA.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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