Longitudinal associations between prepubertal childhood total energy and macronutrient intakes and subsequent puberty timing in UK boys and girls.

Purpose: Early puberty is associated with adverse health outcomes. To identify potential modifiable factors for puberty timing, we examined the associations of prepubertal childhood macronutrient intakes with puberty timing in boys and girls. Methods: In the Avon Longitudinal Study of Parents and Ch...

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Publicado en:European Journal of Nutrition Vol. 61; no. 1; pp. 157 - 168
Autores principales: Cheng, Tuck Seng, Sharp, Stephen J., Brage, Soren, Emmett, Pauline M., Forouhi, Nita G., Ong, Ken K.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Feb2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2022
      vid: 61
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-021-02629-6
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        atl: Longitudinal associations between prepubertal childhood total energy and macronutrient intakes and subsequent puberty timing in UK boys and girls.
      aug:
        au:
          Cheng, Tuck Seng
          Sharp, Stephen J.
          Brage, Soren
          Emmett, Pauline M.
          Forouhi, Nita G.
          Ong, Ken K.
        affil: MRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge Biomedical Campus Box 285, CB2 0QQ, Cambridge, UK
      sug:
        subj:
          Macronutrients
          Food Intake In Infancy and Childhood
          Energy Intake In Infancy and Childhood
          Puberty, Precocious Risk Factors
          Risk Assessment
          Human
          Male
          Female
          Child
          Adolescence
          United Kingdom
          Secondary Analysis
          Linear Regression
          Questionnaires
          Age Factors
          Body Height
          Dietary Proteins
          Dietary Carbohydrates
          Dietary Fats
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Purpose: Early puberty is associated with adverse health outcomes. To identify potential modifiable factors for puberty timing, we examined the associations of prepubertal childhood macronutrient intakes with puberty timing in boys and girls. Methods: In the Avon Longitudinal Study of Parents and Children, macronutrient intakes at age 6 years were predicted using random intercepts linear regression models of dietary data at 3, 4, 7 (assessed by food frequency questionnaires) and 7.5 years (by 3-day food diaries). Timings of puberty onset (Tanner stage 2 genital or breast (B2) development) and puberty completion (voice breaking (VB) or menarche) were calculated from annual parental and child reports at 8–17 years. Age at peak height velocity (PHV) was derived from repeated height measurements at 5–20 years. Linear regression models were fit to estimate the associations of total energy (TEI) and macronutrient intakes (carbohydrate, fat, protein) with puberty timing traits, adjusting for maternal and infant characteristics. Results: Among 3811 boys, higher TEI, but no macronutrient, was associated with earlier VB. Among 3919 girls, higher TEI was associated with earlier ages at B2, PHV, and menarche. Higher protein intake but not carbohydrate or fat intake (in energy partition models) and substitution of dietary protein for carbohydrate (in nutrient density and residual models) was associated with earlier B2, PHV, and menarche in girls. Findings were not attenuated on additional adjustment for body fat percentage during adolescence. Conclusions: These findings suggest habitual total energy intakes in children, and protein intakes in girls, as potential modifiable determinants of puberty timing.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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