Adolescent novelty seeking is associated with greater ventral striatal and prefrontal brain response during evaluation of risk and reward.
Adolescence is a period during which reward sensitivity is heightened. Studies suggest that there are individual differences in adolescent reward-seeking behavior, attributable to a variety of factors, including temperament. This study investigated the neurobiological underpinnings of risk and rewar...
| Published in: | Cognitive, Affective & Behavioral Neuroscience Vol. 22; no. 1; pp. 123 - 134 |
|---|---|
| Main Authors: | , , , , |
| Format: | diagnostic images pictorial research tables/charts Journal Article |
| Published: |
Springer Nature
Feb2022
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=154881096&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 154881096 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307026 NA4 jtl: Cognitive, Affective & Behavioral Neuroscience issn: 15307026 maglogo: N pubinfo: dt: Feb2022 vid: 22 iid: 1 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 154881096 151715935 154881096 154881096 10.3758/s13415-021-00937-2 154881096 ppf: 123 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Adolescent novelty seeking is associated with greater ventral striatal and prefrontal brain response during evaluation of risk and reward. aug: au: Del Giacco, Amanda C. Jones, Scott A. Morales, Angelica M. Kliamovich, Dakota Nagel, Bonnie J. affil: Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA sug: subj: Temperament Magnetic Resonance Imaging Methods Reward Risk Taking Behavior Brain Physiology Human Adolescence Questionnaires Male Female Child Task Performance and Analysis Regression Adolescent: 13-18 years Child: 6-12 years Male Female ab: Adolescence is a period during which reward sensitivity is heightened. Studies suggest that there are individual differences in adolescent reward-seeking behavior, attributable to a variety of factors, including temperament. This study investigated the neurobiological underpinnings of risk and reward evaluation as they relate to self-reported pleasure derived from novel experiences on the revised Early Adolescent Temperament Questionnaire (EATQ-R). Healthy participants (N = 265, ~50% male), aged 12-17 years, underwent functional magnetic resonance imaging during a modified Wheel of Fortune task, where they evaluated choices with varying probability of winning different monetary rewards. Across all participants, there was increased brain response in salience, reward, and cognitive control circuitry when evaluating choices with larger (compared with moderate) difference in risk/reward. Whole brain and a priori region-of-interest regression analyses revealed that individuals reporting higher novelty seeking had greater activation in bilateral ventral striatum, left middle frontal gyrus, and bilateral posterior cingulate cortex when evaluating the choices for largest difference in risk/reward. These novelty seeking associations with brain response were seen in the absence of temperament-related differences in decision-making behavior. Thus, while heightened novelty seeking in adolescents might be associated with greater neural sensitivity to risk/reward, accompanying increased activation in cognitive control regions might regulate reward-driven risk-taking behavior. More research is needed to determine whether individual differences in brain activation associated with novelty seeking are related to decision making in more ecologically valid settings. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|