Neglected analytes in the 24-h urine: ammonium and sulfate.

Purpose Of Review: Evaluation of the kidney stone patient includes measurement of 24 h urine chemistries. This review summarizes the application of physiologic principles to the interpretation of urine chemistries, using sulfate and ammonium to estimate diet acid load, and the renal response.Recent...

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Publicado en:Current Opinion in Nephrology & Hypertension Vol. 31; no. 2; pp. 168 - 175
Autor principal: Asplin, John R.
Formato: review Journal Article
Publicado: Lippincott Williams & Wilkins Mar2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2022
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      pub: Lippincott Williams & Wilkins
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        atl: Neglected analytes in the 24-h urine: ammonium and sulfate.
      aug:
        au: Asplin, John R.
      sug:
        subj:
          Kidney Calculi
          Quaternary Ammonium Compounds
          Sulfates
          Male
          Female
          Kidney
          Hydrogen-Ion Concentration
          Scales
          Male
          Female
      ab: Purpose Of Review: Evaluation of the kidney stone patient includes measurement of 24 h urine chemistries. This review summarizes the application of physiologic principles to the interpretation of urine chemistries, using sulfate and ammonium to estimate diet acid load, and the renal response.Recent Findings: There has been increased recognition of the need to measure urine ammonium excretion in the clinical setting in order to understand renal acid excretion. Some 24 h urine kidney stone panels include ammonium measurements, providing an opportunity to apply this measurement to clinical practice. In order to better interpret ammonium excretion, one needs an estimate of dietary acid load to understand the driving forces for ammonium excretion. Sulfate is also included in some kidney stone panels and functions as an estimate of diet acid load. Combining these analytes with urine pH, the clinician can quickly estimate dietary stone risk as well as potential bowel disease, acidification disorders, and the presence of urease producing bacteria; all of which can affect stone risk.Summary: Measurement of ammonium and sulfate excretion along with urine pH provide important insights into the acid/alkali content of diet, presence and severity of bowel disease, presence of renal acidification disorders, and urinary infection.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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