Performance of an algorithm for diagnosing acute cholecystitis using clinical and sonographic parameters.

Purpose: Identify an algorithm using clinical and ultrasound (US) parameters with high diagnostic performance for acute cholecystitis. Methods: Consecutive emergency department (ED) patients from 4/1/2019 to 12/31/2019 were retrospectively reviewed to record non-US parameters and make US observation...

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Publicado en:Abdominal Radiology Vol. 47; no. 2; pp. 576 - 586
Autores principales: Patel, Maitray D., Sill, Andrew P., Dahiya, Nirvikar, Chen, Frederick, Eversman, William G., Kriegshauser, J. Scott, Young, Scott W.
Formato: algorithm diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Feb2022
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2022
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00261-021-03384-2
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        atl: Performance of an algorithm for diagnosing acute cholecystitis using clinical and sonographic parameters.
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        au:
          Patel, Maitray D.
          Sill, Andrew P.
          Dahiya, Nirvikar
          Chen, Frederick
          Eversman, William G.
          Kriegshauser, J. Scott
          Young, Scott W.
        affil: Department of Radiology, Mayo Clinic Arizona, 5777 E. Mayo Blvd, 85054, Phoenix, AZ, USA
      sug:
        subj:
          Algorithms Evaluation
          Acute Disease Diagnosis
          Cholecystitis Diagnosis
          Sensitivity and Specificity Evaluation
          Diagnosis, Computer Assisted Methods
          Physical Examination
          Hematologic Tests
          Acute Disease Ultrasonography
          Cholecystitis Ultrasonography
          Human
          Emergency Patients
          Retrospective Design
          Predictive Value of Tests
          Descriptive Statistics
          Male
          Female
          Adult
          Middle Age
          Aged
          Chronic Disease Diagnosis
          Cholecystitis Pathology
          Radiologists
          Comparative Studies
          Emergency Service
          Record Review
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: Identify an algorithm using clinical and ultrasound (US) parameters with high diagnostic performance for acute cholecystitis. Methods: Consecutive emergency department (ED) patients from 4/1/2019 to 12/31/2019 were retrospectively reviewed to record non-US parameters and make US observations. Outcomes were categorized as either: (1) acute cholecystitis; or (2) negative acute cholecystitis. Pivot tables identified parameter combinations either not found with acute cholecystitis or with predictive value for acute cholecystitis to establish the algorithm. US Division radiologists finalized an US report prior to ED disposition without use of the algorithm. Radiologist impression and algorithm prediction for acute cholecystitis were categorized as either (1) acute cholecystitis; (2) negative acute cholecystitis; or (3) inconclusive. Results: Three hundred and sixty-six studies on 357 patients (mean age, 51 yrs ± 20 yrs; 215 women) met the inclusion criteria. 10.9% (40/366) of US studies had acute cholecystitis, 12.6% (46/366) had pathologically identified chronic cholecystitis without acute cholecystitis, and 76.5% (280/366) were negative acute cholecystitis. Algorithm compared to radiologist diagnostic performance was as follows: (1) sensitivity: 90.0% vs. 55.0%, p < 0.001; (2) augmented sensitivity (defined as when inconclusive categorization is considered consistent with acute cholecystitis): 100% vs. 85.0%, p < 0.001; (3) specificity: 93.6% vs. 94.8%, p = 0.50; (4) diagnostic rate (opposite of inconclusive rate): 96.4% vs. 93.2%, p = 0.04; (5) adverse outcome rate: 0.0% vs. 1.6%, p undefined. Conclusion: For acute cholecystitis, an algorithm using non-binary ultrasound and clinical assessments had higher sensitivity, higher diagnostic rate, and fewer adverse outcomes, than subspecialty radiologist impressions.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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