Latent profiles of autism symptoms in children and adolescents with Down syndrome.
Background: Down syndrome (DS) is associated with elevated rates of autism spectrum disorder (ASD) and autism symptomatology. To better characterise heterogeneity in ASD symptomatology in DS, profiles of caregiver‐reported ASD symptoms were modelled for children and adolescents with DS. Methods: Par...
| Published in: | Journal of Intellectual Disability Research Vol. 66; no. 3; pp. 265 - 282 |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Mar2022
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155056753&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155056753 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09642633 EUL jtl: Journal of Intellectual Disability Research issn: 09642633 maglogo: Y pubinfo: dt: Mar2022 vid: 66 iid: 3 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 155056753 154472300 155056753 155056753 10.1111/jir.12910 155056753 ppf: 265 ppct: 17 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Latent profiles of autism symptoms in children and adolescents with Down syndrome. aug: au: Fidler, D. J. Prince, M. A. Van Deusen, K. Esbensen, A. J. Thurman, A. J. Abbeduto, L. Patel, L. Mervis, C. Schworer, E. K. Lee, N. R. Edgin, J. O. Hepburn, S. Davis, S. Daunhauer, L. A. affil: Human Development and Family Studies, Colorado State University, Fort Collins CO,, USA sug: subj: Autism Spectrum Disorder Symptoms Autism Spectrum Disorder Symptoms Down Syndrome In Adolescence Human Female Male Child Adolescence Scales Communication Motivation Cognition Risk Assessment Probability Sociodemographic Factors Questionnaires Latent Structure Analysis Descriptive Statistics Child: 6-12 years Adolescent: 13-18 years Female Male ab: Background: Down syndrome (DS) is associated with elevated rates of autism spectrum disorder (ASD) and autism symptomatology. To better characterise heterogeneity in ASD symptomatology in DS, profiles of caregiver‐reported ASD symptoms were modelled for children and adolescents with DS. Methods: Participants (n = 125) were recruited through several multi‐site research studies on cognition and language in DS. Using the Social Responsiveness Scale‐2 (SRS‐2; Constantino and Gruber 2012), two latent profile analyses (LPA) were performed, one on the broad composite scores of social communication and interaction and restricted interests and repetitive behaviour, and a second on the four social dimensions of social communication, social motivation, social awareness, and social cognition. Results: A three‐profile model was the best fit for both analyses, with each analysis yielding a low ASD symptom profile, an elevated or mixed ASD symptom profile and a high ASD symptom profile. Associations were observed between profile probability scores and IQ, the number of co‐occurring biomedical conditions reported, sex, and SRS‐2 form. Conclusions: Characterising heterogeneity in ASD symptom profiles can inform more personalised supports in this population, and implications for potential therapeutic approaches for individuals with DS are discussed. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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