The Predictive Value of ACR TI-RADS Classification for Central Lymph Node Metastasis of Papillary Thyroid Carcinoma: A Retrospective Study.

Background. The aim of this retrospective study was to evaluate the risk factors for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC), according to the guidelines of the 2017 Thyroid Imaging Report and Data System (TI-RADS) published by the American College of Radiology (ACR...

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Published in:International Journal of Endocrinology pp. 1 - 7
Main Authors: Zhong, Minying, Zhang, Zhaoming, Xiao, Yisheng, He, Yanping, Chen, Yongyu, Huang, WeiJun, Lu, Liping
Format: Journal Article
Published: Wiley-Blackwell 2/7/2022
Online Access:View this record in EBSCOhost
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      jtl: International Journal of Endocrinology
      issn: 16878337
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      dt: 2/7/2022
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        155106116
        10.1155/2022/4412725
        155106116
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        atl: The Predictive Value of ACR TI-RADS Classification for Central Lymph Node Metastasis of Papillary Thyroid Carcinoma: A Retrospective Study.
      aug:
        au:
          Zhong, Minying
          Zhang, Zhaoming
          Xiao, Yisheng
          He, Yanping
          Chen, Yongyu
          Huang, WeiJun
          Lu, Liping
        affil: Department of Ultrasound, The First People's Hospital of Foshan, Foshan 528000, China
      sug:
      ab: Background. The aim of this retrospective study was to evaluate the risk factors for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC), according to the guidelines of the 2017 Thyroid Imaging Report and Data System (TI-RADS) published by the American College of Radiology (ACR). Methods. This study included a retrospective analysis of 844 patients with PTC who were pathologically diagnosed, treated with central lymph node dissection, and divided into CLNM and nonmetastatic groups. Univariate and multivariate analyses were performed to determine the relationship between the TI-RADS score and CLNM. Results. Among 844 patients, 439 developed CLNM, with a metastasis rate of 52% and a TI-RADS score of 9.42 ± 2.262, which were higher than those of the non-CLNM group (P < 0.05). Univariate analysis demonstrated that the sex, location, maximum diameter of the nodule, multifocality, margin, shape, calcification, and TI-RADS score were related to CLNM (P < 0.05 for all). However, multivariate logistic regression analysis demonstrated that female, maximum diameter of the nodule, multifocality, a taller-than-wide shape, and high TI-RADS score were the independent risk factors for CLNM (P < 0.05 for all). Conclusion. The TI-RADS score combined with sex, nodule size, shape, and multifocality has a certain predictive effect on CLNM, which can provide a reference to the clinicians for further treatment strategies.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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