Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial.

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. As a result of the rapid progression and severity of the disease, people with ALS experience loss of functionality and independence. Furthermore, it has already been described presence of autonomic dysfunction. Despite the increasin...

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Publicado en:BioMed Research International pp. 1 - 12
Autores principales: Silveira, Ana C., Moraes, Íbis A. P., Vidigal, Giovanna P., Simcsik, Amanda O., Rosa, Renata M., Favero, Francis M., Fernandes, Susi M. S., Garner, David M., Araújo, Luciano V., Massa, Marcelo, Vanderlei, Luiz C. M., Silva, Talita D., Monteiro, Carlos B. M.
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2/9/2022
Acceso en línea:Ver este registro en EBSCOhost
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        10.1155/2022/4439681
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        atl: Cardiac Autonomic Modulation in Subjects with Amyotrophic Lateral Sclerosis (ALS) during an Upper Limb Virtual Reality Task: A Prospective Control Trial.
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        au:
          Silveira, Ana C.
          Moraes, Íbis A. P.
          Vidigal, Giovanna P.
          Simcsik, Amanda O.
          Rosa, Renata M.
          Favero, Francis M.
          Fernandes, Susi M. S.
          Garner, David M.
          Araújo, Luciano V.
          Massa, Marcelo
          Vanderlei, Luiz C. M.
          Silva, Talita D.
          Monteiro, Carlos B. M.
        affil: Postgraduate Program in Physical Activity Sciences, School of Arts, Science and Humanities of University of São Paulo (EACH-USP), São Paulo, SP 03828-000, Brazil
      sug:
        subj:
          Cardiovascular System Physiology Evaluation
          Autonomic Nervous System Physiology
          Amyotrophic Lateral Sclerosis Rehabilitation
          Upper Extremity
          Virtual Reality Utilization
          Human
          Prospective Studies
          Sitting
          Heart Rate Variability
          Questionnaires
          Scales
          Sympathetic Nervous System
          Parasympathetic Nervous System
          Recovery
      ab: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease. As a result of the rapid progression and severity of the disease, people with ALS experience loss of functionality and independence. Furthermore, it has already been described presence of autonomic dysfunction. Despite the increasing use of virtual reality (VR) in the treatment of different diseases, the use of virtual reality environment as an intervention program for ALS patients is innovative. The benefits and limitations have not yet been proven. Our objective was to evaluate the autonomic function of individuals with amyotrophic lateral sclerosis throughout the virtual reality task. The analysis of autonomic function was completed before, during, and after the virtual reality task using the upper limbs; also, all steps lasted ten minutes in a sitting position. Heart rate variability (HRV) was taken via the Polar® RS800CX cardiofrequencymeter. The following questionnaire was enforced: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS) and Fatigue Severity Scale (FSS). Different types of HRV were revealed for the groups, indicating that the ALS group has reduced HRV, with most of the representative indices of the sympathetic nervous system. Besides, the physiological process of reducing parasympathetic activity from rest to VR activity (vagal withdrawal), with reduction in HF (ms2) and an increase in HR from rest to activity, and a further increase throughout recovery, with withdrawal of sympathetic nervous system, occurs just for the control group (CG), with no alterations between rest, activity, and recovery in individuals with ALS. We could conclude that patients with ALS have the reduction of HRV with the sympathetic predominance when equated to the healthy CG. Besides that, the ALS individuals have no capability to adapt the autonomic nervous system when likened to the CG during therapy based on VR and their recovery.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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