Potentially inappropriate medications and their effect on falls during hospital admission.
Objective to investigate the effect of potentially inappropriate medications (PIMs) on inpatient falls and to identify whether PIMs as defined by STOPPFall or the designated section K for falls of STOPP v2 have a stronger association with inpatient falls when compared to the general tool STOPP v2. M...
| Publicado en: | Age & Ageing Vol. 51; no. 1; pp. 1 - 9 |
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| Autores principales: | , , , , , , |
| Formato: | Artículo |
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Oxford University Press / USA
Jan2022
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=155241232&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 155241232 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00020729 AGA jtl: Age & Ageing issn: 00020729 maglogo: N pubinfo: dt: Jan2022 vid: 51 iid: 1 pid: 622 pub: Oxford University Press / USA artinfo: ui: 155241232 10.1093/ageing/afab205 ppf: 1 ppct: 8 formats: tig: atl: Potentially inappropriate medications and their effect on falls during hospital admission. aug: au: Damoiseaux-Volman, Birgit A Raven, Kimmy Sent, Danielle Medlock, Stephanie Romijn, Johannes A Abu-Hanna, Ameen van der Velde, Nathalie affil: Department of Medical Informatics , Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands Department of Medicine , Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands Section of Geriatric Medicine , Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands su: Retrospective studies Hospital care Hospital care of older people Old age Scientific observation Acquisition of data methodology Confidence intervals Inappropriate prescribing (Medicine) Risk assessment Accidental falls Medical records Descriptive statistics Logistic regression analysis Odds ratio Proportional hazards models sug: subj: Retrospective studies Hospital care Hospital care of older people Old age Scientific observation Acquisition of data methodology Confidence intervals Inappropriate prescribing (Medicine) Risk assessment Accidental falls Medical records Descriptive statistics Logistic regression analysis Odds ratio Proportional hazards models keyword: accidental falls hospital inappropriate prescriptions older people accidental falls hospital inappropriate prescriptions older people ab: Objective to investigate the effect of potentially inappropriate medications (PIMs) on inpatient falls and to identify whether PIMs as defined by STOPPFall or the designated section K for falls of STOPP v2 have a stronger association with inpatient falls when compared to the general tool STOPP v2. Methods a retrospective observational matching study using an electronic health records dataset of patients (≥70 years) admitted to an academic hospital (2015–19), including free text to identify inpatient falls. PIMs were identified using the STOPP v2, section K of STOPP v2 and STOPPFall. We first matched admissions with PIMs to those without PIMs on confounding factors. We then applied multinomial logistic regression analysis and Cox proportional hazards analysis on the matched datasets to identify effects of PIMs on inpatient falls. Results the dataset included 16,678 hospital admissions, with a mean age of 77.2 years. Inpatient falls occurred during 446 (2.7%) admissions. Adjusted odds ratio (OR) (95% confidence interval (CI)) for the association between PIM exposure and falls were 7.9 (6.1–10.3) for STOPP section K, 2.2 (2.0–2.5) for STOPP and 1.4 (1.3–1.5) for STOPPFall. Adjusted hazard ratio (HR) (95% CI) for the effect on time to first fall were 2.8 (2.3–3.5) for STOPP section K, 1.5 (1.3–1.6) for STOPP and 1.3 (1.2–1.5) for STOPPFall. Conclusions we identified an independent association of PIMs on inpatient falls for all applied (de)prescribing tools. The strongest effect was identified for STOPP section K, which is restricted to high-risk medication for falls. Our results suggest that decreasing PIM exposure during hospital stay might benefit fall prevention, but intervention studies are warranted. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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