MRI of focal cortical dysplasia.

Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular...

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Bibliographic Details
Published in:Neuroradiology Vol. 64; no. 3; pp. 443 - 453
Main Authors: Urbach, Horst, Kellner, Elias, Kremers, Nico, Blümcke, Ingmar, Demerath, Theo
Format: diagnostic images review tables/charts Journal Article
Published: Springer Nature Mar2022
Online Access:View this record in EBSCOhost
Description
Summary:Focal cortical dysplasia (FCD) are histopathologically categorized in ILAE type I to III. Mild malformations of cortical development (mMCD) including those with oligodendroglial hyperplasia (MOGHE) are to be integrated into this classification yet. Only FCD type II have distinctive MRI and molecular genetics alterations so far. Subtle FCD including FCD type II located in the depth of a sulcus are often overlooked requiring the use of dedicated sequences (MP2RAGE, FLAWS, EDGE) and/or voxel (VBM)- or surface-based (SBM) postprocessing. The added value of 7 Tesla MRI has to be proven yet.