Prospective association between a Mediterranean-style dietary score in childhood and cardiometabolic risk in young adults from the ALSPAC birth cohort.

Purpose: To investigate the prospective association between a children's relative Mediterranean-style diet score (C-rMED) in childhood and a Cardiometabolic Risk (CMR) score in adolescence/young adulthood in the Avon Longitudinal Study of Parents and Children (ALSPAC). Methods: A C-rMED was calculat...

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Published in:European Journal of Nutrition Vol. 61; no. 2; pp. 737 - 753
Main Authors: Buckland, Genevieve, Taylor, Caroline M., Emmett, Pauline M., Johnson, Laura, Northstone, Kate
Format: research tables/charts Journal Article
Published: Springer Nature Mar2022
Online Access:View this record in EBSCOhost
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      dt: Mar2022
      vid: 61
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-021-02652-7
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        atl: Prospective association between a Mediterranean-style dietary score in childhood and cardiometabolic risk in young adults from the ALSPAC birth cohort.
      aug:
        au:
          Buckland, Genevieve
          Taylor, Caroline M.
          Emmett, Pauline M.
          Johnson, Laura
          Northstone, Kate
        affil: Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK
      sug:
        subj:
          Mediterranean Diet In Infancy and Childhood
          Cardiometabolic Risk Factors In Adolescence
          Human
          Descriptive Statistics
          Data Analysis Software
          Chi Square Test
          Kruskal-Wallis Test
          Confidence Intervals
          Logistic Regression
          Multivariate Analysis
          Odds Ratio
          Male
          Female
          Child
          Adolescence
          Prospective Studies
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Purpose: To investigate the prospective association between a children's relative Mediterranean-style diet score (C-rMED) in childhood and a Cardiometabolic Risk (CMR) score in adolescence/young adulthood in the Avon Longitudinal Study of Parents and Children (ALSPAC). Methods: A C-rMED was calculated at 7, 10 and 13 years from diet diary data. Anthropometric and biochemical data at 17 (N = 1940) and 24 years (N = 1961) were used to calculate CMR scores (sum of sex-specific log-transformed z-scores from triacylglycerol, HDL cholesterol, LDL cholesterol, mean arterial blood pressure, homeostatic model assessment of insulin resistance (HOMA-IR) and fat mass index (FMI)). Adjusted logistic regression models examined associations between C-rMED (categorical and 2-unit increments) and a high CMR score (≥ 80th percentile) and individual CMR components (≥ 80th percentile). Results: A high C-rMED at 13 was associated with a 32% (OR 0.68 (95% CI: 0.49, 0.94)) decreased adjusted odds of having a high CMR score at 24 years, compared to participants with a low C-rMED. No associations were evident at other ages. Tracking of the C-rMED across the three ages showed a stronger negative association between C-rMED and CMR at 24 years when children had at least two high C-rMED scores from 7 to 13 years (adjusted OR: 0.49, 95% CI: 0.29, 0.85), compared to all low scores. FMI and HOMA-IR were the main CMR components contributing to this association. Conclusion: Higher Mediterranean-style diet scores in early adolescence were associated with a better CMR profile in young adults (24 year olds). This underscores the importance of establishing healthy eating habits early in life for future cardiometabolic health.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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