Association Between Motor Task Performance and Hippocampal Atrophy Across Cognitively Unimpaired, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease Individuals.
Hippocampal atrophy is a widely used biomarker for Alzheimer's disease (AD), but the cost, time, and contraindications associated with magnetic resonance imaging (MRI) limit its use. Recent work has shown that a low-cost upper extremity motor task has potential in identifying AD risk. Fifty-four old...
| Publicado en: | Journal of Alzheimer's Disease Vol. 85; no. 4; pp. 1411 - 1418 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155333987&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 155333987 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13872877 FLR jtl: Journal of Alzheimer's Disease issn: 13872877 maglogo: N pubinfo: dt: 2022 vid: 85 iid: 4 pid: 20732 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 155333987 155333987 NLM34958015 155333987 10.3233/JAD-210665 NLM34958015 155333987 ppf: 1411 ppct: 7 formats: tig: atl: Association Between Motor Task Performance and Hippocampal Atrophy Across Cognitively Unimpaired, Amnestic Mild Cognitive Impairment, and Alzheimer's Disease Individuals. aug: au: Schaefer, Sydney Y. Malek-Ahmadi, Michael Hooyman, Andrew King, Jace B. Duff, Kevin affil: School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, USA sug: subj: Alzheimer's Disease Diagnosis Task Performance and Analysis Amnesia Complications Predictive Value of Tests Hippocampus Pathology Atrophy Pathology Magnetic Resonance Imaging Aged Male Female Human Funding Source Aged: 65+ years Male Female ab: Hippocampal atrophy is a widely used biomarker for Alzheimer's disease (AD), but the cost, time, and contraindications associated with magnetic resonance imaging (MRI) limit its use. Recent work has shown that a low-cost upper extremity motor task has potential in identifying AD risk. Fifty-four older adults (15 cognitively unimpaired, 24 amnestic mild cognitive impairment, and 15 AD) completed six motor task trials and a structural MRI. Several measures of motor task performance significantly predicted bilateral hippocampal volume, controlling for age, sex, education, and memory. Thus, this motor task may be an affordable, non-invasive screen for AD risk and progression. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Unknown language: English refInfo: holdings: @attributes: islocal: N |
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