Interventional recanalization therapy in patients with non-cirrhotic, non-malignant portal vein thrombosis: comparison between transjugular versus transhepatic access.

Purpose: To compare the safety and outcome of transjugular versus percutaneous technique in recanalization of non-cirrhotic, non-malignant portal vein thrombosis. Methods: We present a retrospective bicentric analysis of 21 patients with non-cirrhotic, non-malignant PVT, who were treated between 201...

Descripción completa

Detalles Bibliográficos
Publicado en:Abdominal Radiology Vol. 47; no. 3; pp. 1177 - 1187
Autores principales: Mansour, Nabeel, Öcal, Osman, Gerwing, Mirjam, Köhler, Michael, Deniz, Sinan, Heinzow, Hauke, Steib, Christian, Angele, Martin K., Seidensticker, Max, Ricke, Jens, Wildgruber, Moritz
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Mar2022
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=155380775&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 155380775
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        2366004X
        JT14
      jtl: Abdominal Radiology
      issn: 2366004X
      maglogo: N
    pubinfo:
      dt: Mar2022
      vid: 47
      iid: 3
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        155380775
        154633816
        155380775
        155380775
        10.1007/s00261-022-03411-w
        155380775
      ppf: 1177
      ppct: 10
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Interventional recanalization therapy in patients with non-cirrhotic, non-malignant portal vein thrombosis: comparison between transjugular versus transhepatic access.
      aug:
        au:
          Mansour, Nabeel
          Öcal, Osman
          Gerwing, Mirjam
          Köhler, Michael
          Deniz, Sinan
          Heinzow, Hauke
          Steib, Christian
          Angele, Martin K.
          Seidensticker, Max
          Ricke, Jens
          Wildgruber, Moritz
        affil: Department of Radiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany
      sug:
        subj:
          Portal Vein Pathology
          Venous Thrombosis Surgery
          Embolization, Therapeutic Methods
          Radiography, Interventional Methods
          Treatment Outcomes Evaluation
          Human
          Adult
          Middle Age
          Aged
          Retrospective Design
          Record Review
          Portasystemic Shunt, Surgical Methods
          Postoperative Complications
          Blood Loss, Surgical
          Descriptive Statistics
          Multivariate Analysis
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
      ab: Purpose: To compare the safety and outcome of transjugular versus percutaneous technique in recanalization of non-cirrhotic, non-malignant portal vein thrombosis. Methods: We present a retrospective bicentric analysis of 21 patients with non-cirrhotic, non-malignant PVT, who were treated between 2016 and 2021 by interventional recanalization via different access routes (percutaneous [PT] vs. transjugular in transhepatic portosystemic shunt [TIPS] technique). Complication rates with a focus on periprocedural bleeding and patency as well as outcome were compared. Results: Of the 21 patients treated (median age 48 years, range of 19–78), seven (33%) patients had an underlying prothrombotic condition. While 14 (57%) patients were treated for acute PVT, seven (43%) patients had progressive thrombosis with known chronic PVT. Nine patients underwent initial recanalization via PT access and twelve via TIPS technique. There was no significant difference in complete technical success rate according to initial access route (55.5% in PT group vs. 83.3% in TIPS group, p = 0.331). However, creation of an actual TIPS was associated with higher technical success in restoring portal venous flow (86.6% vs. 33.3%, p = 0.030). 13 (61.9%) patients received thrombolysis. Nine (42.8%) patients experienced hemorrhagic complications. In a multivariate analysis, thrombolysis (p = 0.049) and PT access as the first procedure (p = 0.045) were significant risk factors for bleeding. Conclusion: Invasive recanalization of the portal vein in patients with PVT and absence of cirrhosis and malignancy offers a good therapeutic option with high recanalization and patency rates. Bleeding complications result predominantly from a percutaneous access and high amounts of thrombolytics used; therefore, recanalization via TIPS technique should be favored.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N